Results 81 to 90 of about 3,953,318 (310)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The dynamics of evolutionary branching in an ecological model [PDF]
Eco-evolutionary modelling involves the coupling of ecological equations to evolutionary ones. The interaction between ecological dynamics and evolutionary processes is essential to simulating evolutionary branching, a precursor to speciation.
Norbury, J +3 more
core +1 more source
Amplification on Undirected Population Structures: Comets Beat Stars
Scientific Reports, 2017 The fixation probability is the probability that a new mutant introduced in a homogeneous population eventually takes over the entire population.
Andreas Pavlogiannis +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Momentum accelerates evolutionary dynamics
Journal of Physics: ComplexityAbstract We combine momentum from machine learning with evolutionary dynamics, where momentum can be viewed as a simple mechanism of intergenerational memory similar to epigenetic mechanisms. Using information divergences as Lyapunov functions, we show that momentum accelerates the convergence of evolutionary dynamics including the ...
Marc Harper, Joshua Safyan
openaire +4 more sources
Evolutionary Dynamics May Eliminate All Strategies Used in Correlated Equilibria [PDF]
We show on a 4x4 example that many dynamics may eliminate all strategies used in correlated equilibria, and this for an open set of games. This holds for the best-response dynamics, the Brown-von Neumann-Nash dynamics and any monotonic or weakly sign ...
Yannick Viossat
core
State-Policy Dynamics in Evolutionary Games [PDF]
, 2018 International audienceStandard Evolutionary Game Theory framework is a useful tool to study large interacting systems and to understand the strategic behavior of individuals in such complex systems.
Hayel, Yezekael +2 more
core +1 more source
Ecology and Evolution, 2020 Some carnivores are known to survive well in urban habitats, yet the underlying behavioral tactics are poorly understood. One likely explanation for the success in urban habitats might be that carnivores are generalist consumers.
Carolin Scholz +7 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source