Results 111 to 120 of about 234,739 (311)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Escaping Satiation in an Evolutionary Model of Structural Economic Dynamics [PDF]

open access: yes
This paper presents the problem of satiation in relation to a model of evolutionary endogenous growth. The model represents an attempt to provide an evolutionary economic micro foundation to Pasinetti's scheme of the structural economic dynamics of a ...
Esben Sloth Andersen
core  

The dynamics of evolutionary branching in an ecological model

open access: yes
Eco-evolutionary modelling involves the coupling of ecological equations to evolutionary ones. The interaction between ecological dynamics and evolutionary processes is essential to simulating evolutionary branching, a precursor to speciation.
Norbury, J   +3 more
core   +2 more sources

Reconciling the upsides and downsides of migration for evolutionary rescue

open access: yes, 2020
A recommendation – based on reviews by Three anonymous reviewers – of the article: Tomasini, M. and Peischl, S. (2020) When does gene flow facilitate evolutionary rescue? bioRxiv, 622142, ver.
Bank, Claudia
core   +1 more source

Dynamics of cooperation in concurrent games

open access: yesNature Communications
People frequently encounter situations where individually optimal decisions conflict with group interests. To navigate such social dilemmas, they often employ simple heuristics based on direct reciprocity: cooperate when others do and cease cooperation ...
Charlotte S. L. Rossetti   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Replicator Dynamics with Frequency Dependent Stage Games [PDF]

open access: yes
We analyze evolutionary games with replicator dynamics that have frequency dependent stage games. In such an evolutionary game, the payoffs of a strategy at any point in time are functions of the strategy shares given by the players' strategy choices at ...
Esther Bruegger
core  

Evolutionary games on isothermal graphs

open access: yesNature Communications, 2019
The spatial structure of a population is often critical for the evolution of cooperation. Here, Allen and colleagues show that when spatial structure is represented by an isothermal graph, the effective number of neighbors per individual determines ...
Benjamin Allen   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Exploring Evolutionary Economic Geographies [PDF]

open access: yes
Evolutionary approaches in economics have gathered increasing support over the last 25 years. Despite an impressive body of literature, economists are still far from formulating a coherent research paradigm.
David L. Rigby, Jürgen Essletzbichler
core  

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