Results 61 to 70 of about 4,260,217 (298)
How and why we should move beyond natural selection in museums to tackle teleology
Evolution: Education and Outreach, 2023 Background Museum displays commonly use a “VIST” approach (Variation, Inheritance, Selection, and Time) to explain evolution to visitors. I contend that this framework, by focusing narrowly on natural selection, unintentionally reinforces intuitive ...
Shelley L. Smith
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Mechanisms of Large-Scale Evolutionary Trends [PDF]
Evolution, 1994 Large-scale evolutionary trends may result from driving forces or from passive diffusion in bounded spaces. Such trends are persistent directional changes in higher taxa spanning significant periods of geological time; examples include the frequently cited long-term trends in size, complexity, and fitness in life as a whole, as well as trends in lesser
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Against Mechanism: Methodology for an Evolutionary Economics [PDF]
American Journal of Agricultural Economics, 1999 When the first economics departments were proposed at Cambridge and Oxford, the proponents thought acceptance would be improved if economics could be seen as incorporating the methods of physics. The enterprise was premised on the existence of economic laws that describe invariant relationships between events.
A. Allan Schmid, Paul Thompson
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
iScience, 2020 Summary: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spillover infection in December 2019 has caused an unprecedented pandemic. SARS-CoV-2, as other coronaviruses, binds its target cells through the angiotensin-converting enzyme 2 ...
Maya Braun +7 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Applying evolutionary theory to human behaviour: past differences and current debates [PDF]
, 2014 The aim of this paper is to provide non-specialist readers with an introduction to some current controversies surrounding the application of evolutionary theory to human behaviour at the intersection of biology, psychology and anthropology. We review the
Gillian R. Brown +3 more
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BuildingsAgainst the background of profound transformation within the construction industry, the construction industry ecosystem serves as a vital vehicle for regional economic development.
Jinyu Zhao, Xueqian Yao, Lu Zhao
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Evolutionary Mechanisms of Limb Loss in Tetrapods [PDF]
Evolution, 1978 Loss of limbs is one of the most extreme morphological changes in the history of tetrapods, yet it has evolved repeatedly in amphibians, reptiles, birds, and mammals. For none of these groups is there complete knowledge of the mechanisms involved. But on the hypothesis that there is a common set of mechanisms of structural reduction of limbs, shared by
openaire +2 more sources