Results 51 to 60 of about 4,260,217 (298)
Heritability of temperature-mediated flower size plasticity in Arabidopsis thaliana
Quantitative Plant Biology, 2023 Phenotypic plasticity is a heritable trait that provides sessile organisms a strategy to rapidly mitigate negative effects of environmental change. Yet, we have little understanding of the mode of inheritance and genetic architecture of plasticity in ...
Gregory M. Andreou +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Implementation, Elimination of Weakly Dominated Strategies and Evolutionary Dynamics [PDF]
, 2000 This paper studies convergence and stability properties of Sjostrom's (1994) mechanism, under the assumption that boundedly rational players find their way to equilibrium using monotonic evolutionary dynamics and best-reply dynamics.
A. Cabrales +6 more
core +2 more sources
Functional 3-Dimensional Retinal Organoids: Technological Progress and Existing Challenges
Frontiers in Neuroscience, 2021 Stem cell scientists have developed methods for the self-formation of artificial organs, often referred to as organoids. Organoids can be used as model systems for research in multiple biological disciplines.
Meimanat Fathi +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Analysis of Ausubel auctions by means of evolutionary computation [PDF]
, 2005 IEEE Congress on Evolutionary Computation. Edimburgo, 2-5 September 2005The increasing use of auctions has led to a growing interest in the subject.
Sáez, Yago +6 more
core +1 more source
Evolutionary Implications of Environmental Toxicant Exposure
Biomedicines, 2022 Homo sapiens have been exposed to various toxins and harmful compounds that change according to various phases of human evolution. Population genetics studies showed that such exposures lead to adaptive genetic changes; while observing present exposures ...
Giorgia Bolognesi +4 more
doaj +1 more source
Evolutionary Ecology of Prokaryotic Immune Mechanisms [PDF]
Microbiology and Molecular Biology Reviews, 2016 SUMMARYBacteria have a range of distinct immune strategies that provide protection against bacteriophage (phage) infections. While much has been learned about the mechanism of action of these defense strategies, it is less clear why such diversity in defense strategies has evolved.
van Houte, S, Buckling, A, Westra, ER
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source