Results 61 to 70 of about 3,313,584 (302)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The complete mitochondrial genome of Poropanchax normani and phylogenetic studies of Cyprinodontidaes

open access: yesMitochondrial DNA. Part B. Resources, 2021
The complete mitochondrial genome of the Cyprinodontiformes fish Poropanchax normani was studied in this study. The size of the entire mitochondrial genome was 16,878 bp, and the total length of the encoding sequence was 11,435 bp, accounting for 67.75%,
Chuanchen Ren   +7 more
doaj   +1 more source

Grey-box model identification via evolutionary computing [PDF]

open access: yes, 2002
This paper presents an evolutionary grey-box model identification methodology that makes the best use of a priori knowledge on a clear-box model with a global structural representation of the physical system under study, whilst incorporating accurate ...
Y. Li, Li, Y., K.C. Tan, Tan, K.C.
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Genus Petunia (Solanaceae): Evolutionary Synthesis and Taxonomic Review

open access: yesPlants
Many plant groups exhibit complex evolutionary processes, including hybridization, incomplete lineage sorting, and variable evolutionary rates, which make species delimitation challenging.
Luana S. Soares   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Complete Mitochondrial Genomes and Phylogenetic Relationships of Myotis siligorensis and Myotis laniger

open access: yesEcology and Evolution
Bats belong to the order Chiroptera, which represents the second most diverse order among mammals. Bats provide critical ecosystem services through mosquito population control, suppression of agricultural arthropod pests, pollination facilitation, and ...
Xiao‐Die Chen   +4 more
doaj   +1 more source

Complete mitochondrial genome of Procapra picticaudata, with phylogenetic implication

open access: yesMitochondrial DNA. Part B. Resources, 2019
The Tibetan gazelle Procapra picticaudata is endemic to the Tibetan plateau. The species is listed as a Near Threatened (NT) species by the IUCN Red List of Threatened Animals and the Red List of China’s Vertebrates.
Ke-Ji Guo   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The complete mitochondrial genome of Geochelone sulcata

open access: yesMitochondrial DNA. Part B. Resources, 2017
The complete mitochondrial genome of Geochelone sulcata was determined using PCR, Long-PCR with length of 16,692 bp. The genome organization, gene order, and base composition was similar to typical vertebrate.
Qiong Shi   +4 more
doaj   +1 more source

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