Results 31 to 40 of about 122,488 (256)

Changing-Look AGNs or Short-Lived Radio Sources?

Frontiers in Astronomy and Space Sciences, 2017
The evolution of extragalactic radio sources has been a fundamental problem in the study of active galactic nuclei for many years. A standard evolutionary model has been created based on observations of a wide range of radio sources.
Aleksandra Wołowska, Magdalena Kunert-Bajraszewska, Kunal Mooley, Gregg Hallinan   +3 more
doaj   +1 more source

Multi-Objective Quantum Inspired Evolutionary SLM Scheme for PAPR Reduction in Multi-Carrier Modulation

IEEE Access, 2020
As an efficient wireless transmission technology, multi-carrier communication find its way in many applications. However, high peak to average power ratio (PAPR) of the signal degrades the system performance.
Jun Hou, Wei Wang, Yang Zhang, Xinyi Liu, Ying Xie   +4 more
doaj   +1 more source

A conservation planning strategy applied to the evolutionary history of the mantellid frogs of Madagascar

npj Biodiversity, 2023
Phylogenetic diversity is an increasingly applied metric used to maximize the representation of evolutionary history in spatial conservation planning. When following this approach, researchers commonly overlook sites with a relatively higher proportion ...
Miguel R. Ferreira, Francesco Belluardo, Walter Cocca, Angelica Crottini, Sílvia B. Carvalho   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Assessment of Optimization Methods for Aeroacoustic Prediction of Trailing-Edge Interaction Noise in Axisymmetric Jets

Mathematics, 2021
Our concern in this paper is in the fine-tuning of the arbitrary parameters within the upstream turbulence structure for the acoustic spectrum of a rapid-distortion theory (RDT)-based model of trailing-edge noise.
Sarah Stirrat, Mohammed Z. Afsar, Edmondo Minisci   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Genome-Wide Mutation Rate Response to pH Change in the Coral Reef Pathogen Vibrio shilonii AK1

mBio, 2017
Recent application of mutation accumulation techniques combined with whole-genome sequencing (MA/WGS) has greatly promoted studies of spontaneous mutation.
Chloe Strauss, Hongan Long, Caitlyn E. Patterson, Ronald Te, Michael Lynch   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

INSTANTANEOUS FREQUENCY ESTIMATION USING A LEAST SQUARES TIME-FREQUENCY METHOD

Electrica, 2004
We present a method for estimating the instantaneous frequency of a signal. This method involves the calculation of a time-frequency energy density of the signal, then obtaining an instantaneous frequency estimation from this joint density.
Mahmut ÖZTÜRK, Aydın AKAN
doaj   +2 more sources