Results 51 to 60 of about 3,164,796 (323)

A conservation planning strategy applied to the evolutionary history of the mantellid frogs of Madagascar

npj Biodiversity, 2023
Phylogenetic diversity is an increasingly applied metric used to maximize the representation of evolutionary history in spatial conservation planning. When following this approach, researchers commonly overlook sites with a relatively higher proportion ...
Miguel R. Ferreira, Francesco Belluardo, Walter Cocca, Angelica Crottini, Sílvia B. Carvalho   +4 more
doaj   +1 more source

Assessment of Optimization Methods for Aeroacoustic Prediction of Trailing-Edge Interaction Noise in Axisymmetric Jets

Mathematics, 2021
Our concern in this paper is in the fine-tuning of the arbitrary parameters within the upstream turbulence structure for the acoustic spectrum of a rapid-distortion theory (RDT)-based model of trailing-edge noise.
Sarah Stirrat, Mohammed Z. Afsar, Edmondo Minisci   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Determination of design spectrum compatible evolutionary spectra via Monte Carlo peak factor estimation [PDF]

, 2009
The problem of generating ensembles of artificial non-stationary earthquake accelerograms compatible with a given (target) response/design spectrum is cast on a stochastic basis.
Giaralis, A., Spanos, P. D.
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A survey of Low Luminosity Compact sources and its implication for evolution of radio-loud AGNs. II. Optical analysis

, 2010
This is the second in a series of papers concerning a new sample of low luminosity compact (LLC) objects. Here we discuss the optical properties of the sample based on Sloan Digital Sky Survey (SDSS) images and spectra.
A. Labiano, Abazajian, Allen, Allen, Axon, Baldwin, Brotherton, Buttiglione, Buttiglione, Buttiglione, Cardelli, Chambers, Chiaberge, Czerny, De Vries, De Vries, De Vries, Dopita, Evans, Fanti, Fanti, Garofalo, Giroletti, Groves, Groves, Groves, Hardcastle, Hardcastle, Holt, Holt, Hutchings, Kaiser, Kewley, Kewley, Kopylov, Kunert-Bajraszewska, Kunert-Bajraszewska, Labiano, Labiano, Labiano, Labiano, Laing, Levesque, M. Kunert-Bajraszewska, Marecki, Marecki, Massaro, McCarthy, Morganti, O'Dea, O'Dea, Rawlings, Readhead, Spergel, Tasse, Tengstrand, Tremblay, Wilkinson, Willott, Wright   +59 more
core   +1 more source

Modeling the architecture of depolymerase-containing receptor binding proteins in Klebsiella phages [PDF]

, 2019
Klebsiella pneumoniae carries a thick polysaccharide capsule. This highly variable chemical structure plays an important role in its virulence. Many Klebsiella bacteriophages recognize this capsule with a receptor binding protein (RBP) that contains a ...
Briers, Yves, Drulis-Kawa, Zuzanna, Leiman, Petr G, Łątka, Agnieszka   +3 more
core   +2 more sources

INSTANTANEOUS FREQUENCY ESTIMATION USING A LEAST SQUARES TIME-FREQUENCY METHOD

Electrica, 2004
We present a method for estimating the instantaneous frequency of a signal. This method involves the calculation of a time-frequency energy density of the signal, then obtaining an instantaneous frequency estimation from this joint density.
Mahmut ÖZTÜRK, Aydın AKAN
doaj   +2 more sources

Genome-Wide Mutation Rate Response to pH Change in the Coral Reef Pathogen Vibrio shilonii AK1

mBio, 2017
Recent application of mutation accumulation techniques combined with whole-genome sequencing (MA/WGS) has greatly promoted studies of spontaneous mutation.
Chloe Strauss, Hongan Long, Caitlyn E. Patterson, Ronald Te, Michael Lynch   +4 more
doaj   +1 more source