Results 51 to 60 of about 1,952,937 (282)
Genome-Wide Mutation Rate Response to pH Change in the Coral Reef Pathogen
mBio, 2017 Recent application of mutation accumulation techniques combined with whole-genome sequencing (MA/WGS) has greatly promoted studies of spontaneous mutation.
Chloe Strauss +4 more
doaj +1 more source
An evolutionary algorithm for bilevel optimisation of men's team pursuit track cycling
, 2012 Evolutionary Computation is useful in a broad range of practical applications, however currently generalized algorithms tend to be focused upon solving problems in a theoretical domain. We aim to develop a range of generalised algorithms more suited than
Trent Kroeger +3 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Comorbid Analysis of Genes Associated with Autism Spectrum Disorders Reveals Differential Evolutionary Constraints. [PDF]
PLoS ONE, 2016 The burden of comorbidity in Autism Spectrum Disorder (ASD) is substantial. The symptoms of autism overlap with many other human conditions, reflecting common molecular pathologies suggesting that cross-disorder analysis will help prioritize autism gene ...
Maude M David +6 more
doaj +1 more source
An adaptive data structure for evolutionary multi-objective algorithms with unbounded archives
, 2012 Archives have been widely used in evolutionary multi-objective optimization in order to store the optimal points found so far during the optimization process. Usually the size of an archive is bounded which means that the number of points it can store is
Yuen, J. +7 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 1981 Volume 3, Number 3 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1005/thumbnail ...
Spectrum Contributors,
core +1 more source
, 1982 Volume 4, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1006/thumbnail ...
Spectrum Contributors,
core +1 more source
, 1980 Volume 2, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1002/thumbnail ...
Spectrum Contributors,
core +1 more source