Results 61 to 70 of about 6,029,102 (240)
An island based hybrid evolutionary algorithm for optimization [PDF]
, 2008 This is a post-print version of the article - Copyright @ 2008 Springer-VerlagEvolutionary computation has become an important problem solving methodology among the set of search and optimization techniques. Recently, more and more different evolutionary
Yang, S +5 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Experimental test for a co-evolutionary hotspot in a host–parasite interaction
, 2008 Observation: Two independent experiments have shown that freshwater snails (Potamopyrgus antipodarum) collected from the shallow-water margins of a lake are more susceptible to infection by a trematode worm (Microphallus sp.) than snails collected from ...
Dybdahl, Mark F. (author) +3 more
core +1 more source
Application of Multiobjective Evolutionary Techniques for Robust Portfolio Optimization
International Journal of Interactive Multimedia and Artificial Intelligence, 2013 On December 20 of 2012 Sandra García Rodríguez defended his PhD at Carlos III of Madrid (Spain), called: “Application of Multiobjective Techniques for Robust Portfolio Optimization”. This thesis was supervised by Dr. David Quintana Montero and Dr. Inés M.
Sandra Garcia Rodriguez
doaj +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
An evolutionary algorithm for bilevel optimisation of men's team pursuit track cycling
, 2012 Evolutionary Computation is useful in a broad range of practical applications, however currently generalized algorithms tend to be focused upon solving problems in a theoretical domain. We aim to develop a range of generalised algorithms more suited than
Trent Kroeger +3 more
core +1 more source
Evolutionary Computation: Theories, Techniques, and Applications
Applied SciencesEvolutionary computation is now nearly 50 years old, originating with the seminal work of John Holland at the University of Michigan in 1975 which introduced the genetic algorithm [...]
Vincent A. Cicirello
doaj +1 more source
La evolución de técnicas y fenómenos: hacia una explicación de la "confección" del mundo
Crítica, 2019 In recent articles some authors (e.g. Pickering 1989, Hacking 1992) have pointed out a process of gradual adjustment or tailoring between phenomena, models and experimental techniques.
Sergio F. Martínez, Edna Suárez
doaj +1 more source