Results 71 to 80 of about 863,024 (318)

Freedom Giving Birth to Order: Philosophical Reflections on Peirce's Evolutionary Cosmology and its Contemporary Resurrections [PDF]

, 2020
This paper seeks to show that Charles Sanders Peirce's interest in an evolutionary account of the laws of nature is motivated both by his desire to extend the scope of the application of the Principle of Sufficient Reason (PSR) and by his attempt to ...
Nabolsy, Zeyad El
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

For the good of the group? Exploring group-level evolutionary adaptations using multilevel selection theory. [PDF]

, 2008
In this paper, we present an evolutionary framework, multilevel selection theory (MLS), that is highly amenable to existing social psychological theory and empiricism.
O'Gorman, Rick, Sheldon, Kennon M, Wilson, David S   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Ecosystem-Oriented Distributed Evolutionary Computing

, 2012
We create a novel optimisation technique inspired by natural ecosystems, where the optimisation works at two levels: a first optimisation, migration of genes which are distributed in a peer-to-peer network, operating continuously in time; this process ...
Briscoe, Gerard, De Wilde, Philippe
core   +1 more source

Raoul Beunen, Kristof Van Assche, & Martijn Duineveld, Evolutionary Governance Theory: Theory and Applications [PDF]

, 2015
Book ...
LO, Ming Chien
core   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Tradurre evoluzionismi. Due libri di Dan Sperber e Patrick Tort in italiano

Lingue Culture Mediazioni, 2020
Not all Darwinisms are alike. Biological Darwinism is by now an established fact: its basis (first developed in The Origin of Species, 1859), natural selection, seems to have resisted so far to any serious falsification attempt.
Fabio Regattin
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Kant’s Moral Theory Meets Evolutionary Theory [PDF]

Journal of Philosophical Investigations
This paper delves into the intersection between Kant’s moral theory and evolutionary perspectives on personhood. It explores how Kant’s emphasis on rationality in moral agency aligns with evolutionary studies on the development of moral behaviors.
Alireza Mansouri
doaj   +1 more source