Results 81 to 90 of about 863,024 (318)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

RELATIONSHIPS BETWEEN SEXUAL BEHAVIOR AND PERSONALITY IN THE CONTEXT OF SEXUAL DIMORPHISM [PDF]

open access: yesPsihologija, 2009
The aim of this study was to examine the structure and intensity of relation-ships between dimensions of sexual behavior and personal characteristics in the context of sexual dimorphism. The sample included 233 participants (both genders, mean age 29,34).
Bojana Dinic, Goran Knezevic
doaj  

The cell's self-generated “electrome”: The biophysical essence of the immaterial dimension of Life?

open access: yesCommunicative & Integrative Biology, 2016
In the classical “mind-body” wording, “body” is usually associated with the “mass aspect” of living entities and “mind” with the “immaterial” one. Thoughts, consciousness and soul are classified as immaterial.
Arnold De Loof
doaj   +1 more source

(Re‐) Defining evolutionary medicine

open access: yesEcology and Evolution, 2020
The applicability of evolutionary biology principles to diseases has been largely questioned by the medical field. While Evolutionary Medicine (EM) developed in part to lessen this gap, EM is an independent field from both evolution and medicine, whose ...
Jacqueline Moltzau Anderson   +1 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Downright Sexy: Verticality, Implicit Power, and Perceived Physical Attractiveness

open access: yes, 2009
Grounded theory proposes that abstract concepts (e.g., power) are represented by perceptions of vertical space (e.g., up is powerful; down is powerless).
Dionne, Sarah G., Meier, Brian P.
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

THE CONCEPT OF CONTINUOUS CREATION PART II: CONTINUOUS CREATION: TOWARD A RENEWED AND ACTUALIZED CONCEPT

open access: yesZygon, 2020
The renewal of the concept of continuous creation follows two steps: (1) an establishment of the concept of novelty in an exercise of philosophy of nature, as a means of interpreting the scientific discourse concerning the evolution of life; (2 ...
doaj   +2 more sources

On an Evolutionary Foundation of Neuroeconomics [PDF]

open access: yes
Neuroeconomics focuses on brain imaging studies mapping neural responses to choice behavior. Economic theory is concerned with choice behavior but it is silent on neural activities.
Burkhard C. Schipper
core  

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