Results 11 to 20 of about 386,203 (191)

Development and initial validation of the bronchiectasis exacerbation and symptom tool (BEST) [PDF]

, 2020
BACKGROUND: Recurrent bronchiectasis exacerbations are related to deterioration of lung function, progression of the disease, impairment of quality of life, and to an increased mortality.
A Spinou, Adam T. Hill, AJ Mackay, AJ Mackay, AL Quittner, Anthony De Soyza, Arietta Spinou, CB Wilson, CS Haworth, David Araújo, EK Dudgeon, Eva Polverino, Eva Polverino, Irena F Laska, IS Patel, James D. Chalmers, MA Calderazzo, MP Murray, N Kapur, PW Jones, Roland Diel, Sanjay H. Chotirmall, SE Brill, SSC Kon, T McKeever, TA Seemungal, Timothy Aksamit   +26 more
core   +3 more sources

Risk factors for exacerbations and pneumonia in patients with chronic obstructive pulmonary disease: a pooled analysis. [PDF]

, 2020
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) are at risk of exacerbations and pneumonia; how the risk factors interact is unclear.
A Anzueto, B Majed, C Crim, C Crim, C Crim, CR Simpson, DB DiBardino, DB Rubin, DE Niewoehner, DT Phung, EF Wouters, FJ Martinez, Global Initiative for Chronic Obstructive Lung Disease, GS Collins, GT Ferguson, H Müllerova, H Müllerova, J Kim, J Vestbo, J Zhang, JA Wedzicha, JR Hurst, KM Kew, M Hamer, MB Drummond, MC Harpsøe, MI Restrepo, MT Dransfield, MT García Sanz, P Calverley, P Ernst, PM Calverley, RL DiSantostefano, RL DiSantostefano, S Siederer, S Singh, SD Neidich, SH Lin, SJ Pascoe, WM Chatila, Y Çolak, Y-F Wei, YS Jo   +42 more
core   +2 more sources

The Association Between Rate and Severity of Exacerbations in Chronic Obstructive Pulmonary Disease: An Application of a Joint Frailty-Logistic Model. [PDF]

, 2016
Exacerbations are a hallmark of chronic obstructive pulmonary disease (COPD). Evidence suggests the presence of substantial between-individual variability (heterogeneity) in exacerbation rates.
Albert, Richard, Connett, John E, Criner, Gerard, Han, Meilan, Lazarus, Stephen, Martinez, Fernando, Sadatsafavi, Mohsen, Sin, Don D, Zafari, Zafar   +8 more
core   +1 more source

Early versus delayed pulmonary rehabilitation:A randomized controlled trial – Can we do it? [PDF]

, 2018
Providing outpatient pulmonary rehabilitation (PR) following hospitalization for an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has been found to improve exercise capacity, quality of life and a reduction in unplanned hospital ...
Revitt, Olivia, Sewell, Louise, Singh, Sally   +2 more
core   +1 more source

Effect of fixed-dose subcutaneous reslizumab on asthma exacerbations in patients with severe uncontrolled asthma and corticosteroid sparing in patients with oral corticosteroid-dependent asthma : results from two phase 3, randomised, double-blind, placebo-controlled trials [PDF]

, 2020
BACKGROUND: Reslizumab 3 mg/kg administered intravenously is approved for the treatment of severe eosinophilic asthma. We assessed the safety and efficacy of subcutaneous reslizumab 110 mg in two trials in patients with uncontrolled severe asthma and ...
Adir, Yochai, Bernstein, Jonathan A, Brusselle, Guy, Castro, Mario, Garin, Margaret, Hickey, Lisa, Humbert, Marc, Jacobs, Joshua, Marsteller, Douglas A, Maspero, Jorge Fernando, McElhattan, Jennifer, Murphy, Kevin, Vanlandingham, Rebecca, Virchow, J Christian   +13 more
core   +1 more source

Four patients with a history of acute exacerbations of COPD: implementing the CHEST/Canadian Thoracic Society guidelines for preventing exacerbations [PDF]

, 2015
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if ...
A Singanayagam, AJ Crockett, AL Ries, AM Yohannes, C Fletcher, CE Bucknall, CM Fletcher, CP Hersh, D Brooks, DD Marciniuk, F Maltais, FA Cleutjens, G Guyatt, GJ Criner, J Chong, J Pynoos, J Strijbos, JJ Soler-Cataluna, JW Dodd, K Gruffydd-Jones, K Rockwood, K Rockwood, KH Groenewegen, L Cheyne, L Lahousse, L Puente-Maestu, LP Fried, LS Bickford, M Guell, M Stickland, M Zwerink, MM Ball, P Almagro, PG Gibson, PW Jones, S Hull, SK Park, SP Newman, T Bodenheimer, T Lee, TM Wilkinson, VS Fan, World Health Organization, Y Lacasse   +43 more
core   +1 more source

Predictors of Suboptimal Peak Inspiratory Flow in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Clinical Practice [PDF]

Tuberculosis and Respiratory Diseases
Background Incorrect inhalation technique is a primary cause of therapeutic failure in chronic obstructive pulmonary disease (COPD), leading to increased exacerbation frequency.
Natalia V. Trushenko, Baina B. Lavginova, Svetlana Yu. Chikina, Natalia E. Obukhova, Iuliia A. Levina, Fedor D. Tkachenko, Galina V. Nekludova, Zamira M. Merzhoeva, Sergey N. Avdeev   +8 more
doaj   +1 more source

Single-inhaler fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol plus umeclidinium using two inhalers for chronic obstructive pulmonary disease: A randomized non-inferiority study [PDF]

, 2018
Background: Single-inhaler fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) 100/62.5/25 μg has been shown to improve lung function and health status, and reduce exacerbations, versus budesonide/formoterol in patients with chronic obstructive ...
Birk, Ruby, Brealey, Noushin, Bremner, Peter R, Ismaila, Afisi S, Lipson, David A, Zhu, Chang-Qing   +5 more
core   +2 more sources

Exacerbations of COPD [PDF]

European Respiratory Review, 2018
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer from exacerbations. Severe exacerbations are related to a significantly worse survival outcome.
Christian Viniol, Claus F. Vogelmeier
openaire   +3 more sources

Observational study on the impact of initiating tiotropium alone versus tiotropium with fluticasone propionate/salmeterol combination therapy on outcomes and costs in chronic obstructive pulmonary disease

Respiratory Research, 2012
Background This retrospective cohort study compared the risks of exacerbations and COPD-related healthcare costs between patients with chronic obstructive pulmonary disease (COPD) initiating tiotropium (TIO) alone and patients initiating triple therapy ...
Chatterjee Arjun, Shah Manan, D'Souza Anna O, Bechtel Benno, Crater Glenn, Dalal Anand A   +5 more
doaj   +1 more source