Results 41 to 50 of about 283,135 (312)
American Journal of Respiratory and Critical Care Medicine, 2018 Asthma is a very common disease in adults, including in those who work outside the home. Work-related asthma refers to asthma that is either caused by or worsened by something at work. It is very important to know whether someone has work-related asthma because there are specific ways to manage it.
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Asthma outcomes: Exacerbations [PDF]
Journal of Allergy and Clinical Immunology, 2012 The goals of asthma treatment include preventing recurrent exacerbations. Yet there is no consensus about the terminology for describing or defining “exacerbation,” or about how to characterize an episode’s severity.
Anne, Fuhlbrigge +10 more
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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Percent Recovery Index Predicts Poor Asthma Control and Exacerbation in Adults
Journal of Asthma and Allergy, 2023 Lisha Kuang,1,* Cheng Ren,2,* Xiuqing Liao,2 Xiaobin Zhang,2 Xuegang Zhou2 1Department of Health Management Center, Chongqing University Fuling Hospital, Chongqing, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine,
Kuang L, Ren C, Liao X, Zhang X, Zhou X
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
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The disruptive effects of COPD exacerbation-associated factors on epithelial repair responses
Frontiers in ImmunologyIntroductionExacerbations of chronic obstructive pulmonary disease (COPD) increase mortality risk and can lead to accelerated loss of lung function. The increased inflammatory response during exacerbations contributes to worsening of airflow limitation ...
Rosa K. Kortekaas +12 more
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Key toolkits of non-pharmacological management in COPD: during and beyond COVID-19
Frontiers in Bioscience-Landmark, 2021 Individuals with COPD are at higher risk of severe disease and mortality if they contract COVID-19. Shielding and social distancing have negatively impacted the delivery of routine care for COPD patients, which should be maintained to avoid further ...
Jaber S. Alqahtani +4 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
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International Journal of COPD, 2022 Tai Joon An,1 Yeun Jie Yoo,2 Jeong Uk Lim,1 Wan Seo,3 Chan Kwon Park,1 Chin Kook Rhee,4 Hyoung Kyu Yoon1 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St.
An TJ +6 more
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Viruses and asthma exacerbations [PDF]
Thorax, 1998 For many years general opinion has been that upper respiratory viruses were the cause of the common cold but were able to produce serious complications only in infants, the elderly, and immunocompromised subjects. Although a connection between upper respiratory infections and asthma had long been recognised, the potential importance of the association ...
N G, Papadopoulos, S L, Johnston
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