Results 51 to 60 of about 261,950 (315)

Percent Recovery Index Predicts Poor Asthma Control and Exacerbation in Adults

open access: yesJournal of Asthma and Allergy, 2023
Lisha Kuang,1,* Cheng Ren,2,* Xiuqing Liao,2 Xiaobin Zhang,2 Xuegang Zhou2 1Department of Health Management Center, Chongqing University Fuling Hospital, Chongqing, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine,
Kuang L, Ren C, Liao X, Zhang X, Zhou X
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The disruptive effects of COPD exacerbation-associated factors on epithelial repair responses

open access: yesFrontiers in Immunology
IntroductionExacerbations of chronic obstructive pulmonary disease (COPD) increase mortality risk and can lead to accelerated loss of lung function. The increased inflammatory response during exacerbations contributes to worsening of airflow limitation ...
Rosa K. Kortekaas   +12 more
doaj   +1 more source

Key toolkits of non-pharmacological management in COPD: during and beyond COVID-19

open access: yesFrontiers in Bioscience-Landmark, 2021
Individuals with COPD are at higher risk of severe disease and mortality if they contract COVID-19. Shielding and social distancing have negatively impacted the delivery of routine care for COPD patients, which should be maintained to avoid further ...
Jaber S. Alqahtani   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Diaphragm Ultrasound is an Imaging Biomarker that Distinguishes Exacerbation Status from Stable Chronic Obstructive Pulmonary Disease

open access: yesInternational Journal of COPD, 2022
Tai Joon An,1 Yeun Jie Yoo,2 Jeong Uk Lim,1 Wan Seo,3 Chan Kwon Park,1 Chin Kook Rhee,4 Hyoung Kyu Yoon1 1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St.
An TJ   +6 more
doaj  

Comparison of clinical features between patients with acute exacerbation of idiopathic interstitial pneumonia and collagen vascular disease-associated interstitial pneumonia [PDF]

open access: yes, 2023
Acute exacerbation (AE) of interstitial pneumonia (IP) shows poor prognosis, due to the typical histological pattern of diffuse alveolar damage superimposed upon lung fibrosis.
Fujii, Hiroaki   +15 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

B-type natriuretic peptide as a predictor of severity in admitted patients with acute exacerbation of COPD

open access: yesThe Egyptian Journal of Bronchology, 2019
Background patients with acute AECOPD show an abrupt worsening of baseline ventricular function and pulmonary hypertension, using clear predictors or markers for severity in such patients is critical to be early stratified and properly managed.
Nasser K. Abdelnaby   +2 more
doaj   +1 more source

Management of exacerbations of COPD [PDF]

open access: yesMedicine, 2003
Exacerbations of chronic obstructive pulmonary disease (COPD) are an important cause of morbidity and mortality in the condition, and their incidence increases with its severity. Some patients suffer frequent exacerbations leading to hospital admission, with considerable impact on their quality of life and activities of daily living. COPD exacerbations
Seemungal, Terence, Wedzicha, Jadwiga A
openaire   +2 more sources

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