Results 41 to 50 of about 242,368 (323)

Mometasone/Indacaterol/Glycopyrronium (MF/IND/GLY) and MF/IND at Different MF Strengths versus Fluticasone Propionate/Salmeterol Xinafoate (FLU/SAL) and FLU/SAL+ Tiotropium in Patients with Asthma

Journal of Asthma and Allergy, 2023
Richard N van Zyl-Smit,1 Kenneth R Chapman,2 Huib AM Kerstjens,3 Christian Gessner,4 Hironori Sagara,5 Ana-Maria Tanase,6 Motoi Hosoe,6 Abhijit Pethe,7 David Lawrence,6 Hanns-Christian Tillmann,8 Peter D’Andrea7 1Division of Pulmonology and UCT Lung ...
van Zyl-Smit RN, Chapman KR, Kerstjens HAM, Gessner C, Sagara H, Tanase AM, Hosoe M, Pethe A, Lawrence D, Tillmann HC, D'Andrea P   +10 more
doaj  

Impact of sarcopenia on chemotherapy‐triggered exacerbation of interstitial lung disease in patients with non‐small cell lung cancer

Thoracic Cancer, 2022
Background While recent evidence has suggested that sarcopenia could predict chemotoxicity, its association with chemotherapy‐triggered interstitial lung disease (ILD) exacerbations has yet to be investigated.
Ryota Kikuchi, Hiroyuki Takoi, Mayuko Ishiwari, Kazutoshi Toriyama, Yuta Kono, Yuki Togashi, Shinji Abe   +6 more
doaj   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Characterisation of exacerbation risk and exacerbator phenotypes in the POET-COPD trial [PDF]

Respiratory Research, 2013
Abstract Background Data examining the characteristics of patients with frequent exacerbations of chronic obstructive pulmonary disease (COPD) and associated hospitalisations and mortality are scarce. Methods Post-hoc analysis of the Prevention Of ...
Kai M. Beeh, Thomas Glaab, Susanne Stowasser, Hendrik Schmidt, FABBRI, Leonardo, Klaus F. Rabe, Claus F. Vogelmeier   +6 more
openaire   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Assessment of serum electrolytes (sodium, potassium, and ionized calcium) during chronic obstructive pulmonary disease exacerbation

Egyptian Journal of Chest Disease and Tuberculosis, 2019
Background Chronic obstructive pulmonary disease (COPD) is the third leading universal cause of mortality. Although chronic obstructive pulmonary disorder is primarily a chronic disease, a great number of patients complain of exacerbations.
Rasha M Hendy, Marwa E El-Naggar
doaj   +1 more source

Acute exacerbation of COPD [PDF]

Respirology, 2016
AbstractThe literature of acute exacerbation of chronic obstructive pulmonary disease (COPD) is fast expanding. This review focuses on several aspects of acute exacerbation of COPD (AECOPD) including epidemiology, diagnosis and management. COPD poses a major health and economic burden in the Asia‐Pacific region, as it does worldwide. Triggering factors
David S.C. Hui, Fanny W.S. Ko, John R. Goddard, Ian A. Yang, Ka Pang Chan, David W. Reid, David W. Reid, Janet G. Shaw   +7 more
openaire   +4 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Imperfect ImaGANation: Implications of GANs Exacerbating Biases on Facial Data Augmentation and Snapchat Selfie Lenses [PDF]

arXiv, 2020
In this paper, we show that popular Generative Adversarial Networks (GANs) exacerbate biases along the axes of gender and skin tone when given a skewed distribution of face-shots. While practitioners celebrate synthetic data generation using GANs as an economical way to augment data for training data-hungry machine learning models, it is unclear ...
arxiv  

Machine Translationese: Effects of Algorithmic Bias on Linguistic Complexity in Machine Translation [PDF]

arXiv, 2021
Recent studies in the field of Machine Translation (MT) and Natural Language Processing (NLP) have shown that existing models amplify biases observed in the training data. The amplification of biases in language technology has mainly been examined with respect to specific phenomena, such as gender bias. In this work, we go beyond the study of gender in
arxiv