Results 51 to 60 of about 434,643 (342)
Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils [PDF]
, 2017 INTRODUCTION: Asthma with adult onset and elevated blood eosinophils is a difficult-to-treat subgroup. This post hoc analysis evaluated reslizumab, an anti-interleukin-5 monoclonal antibody, in patients with late-onset eosinophilic asthma.
Brusselle, Guy +3 more
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Journal of Asthma and Allergy, 2023 Richard N van Zyl-Smit,1 Kenneth R Chapman,2 Huib AM Kerstjens,3 Christian Gessner,4 Hironori Sagara,5 Ana-Maria Tanase,6 Motoi Hosoe,6 Abhijit Pethe,7 David Lawrence,6 Hanns-Christian Tillmann,8 Peter D’Andrea7 1Division of Pulmonology and UCT Lung ...
van Zyl-Smit RN +10 more
doaj
Medičnì Perspektivi, 2018 Aim of the study – to enhance the diagnostic and treatment tactics of stable COPD patients management at out patient stage by studying the serum AAT. Data of 45 outpatients with COPD (GOLD I-IV) and 20 healthy persons were included into analysis.
K. Yu. Gashynova
doaj +1 more source
Serum Uric Acid in Chronic Obstructive Pulmonary Disease: A Hospital Based Case Control Study [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Airway inflammation and imbalance between oxidant/ anti-oxidant mechanisms are postulated to play a major role in the pathogenesis and exacerbation of Chronic Obstructive Pulmonary Disease (COPD).
Rajlaxmi Sarangi +5 more
doaj +1 more source
Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation [PDF]
, 2017 Purpose Cough is common in chronic obstructive pulmonary disease (COPD) and is associated with frequent exacerbations and increased mortality. Cough increases during acute exacerbations (AE-COPD), representing a possible metric of clinical deterioration.
Crooks, Michael G. +7 more
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Is there a role of viral infection in cystic fibrosis exacerbation in children?
The Turkish Journal of Pediatrics, 2022 Background. Cystic fibrosis (CF) is a degenerative disease distinguished by progressive epithelial secretory gland dysfunction associated with recurrent respiratory tract infections.
Dina H Hamed +3 more
doaj +1 more source
'Exacerbation-free time' to assess the impact of exacerbations in patients with chronic obstructive pulmonary disease (COPD):a prospective observational study [PDF]
, 2018 COPD exacerbations are commonly quantified as rate per year. However, the total amount of time a patient suffers from exacerbations may be stronger related to his or her disease burden than just counting exacerbation episodes.
Akkermans, R P +7 more
core +3 more sources