Results 21 to 30 of about 181,704 (312)

DO IT Trial: vitamin D Outcomes and Interventions in Toddlers - a TARGet Kids! randomized controlled trial. [PDF]

, 2014
BackgroundVitamin D levels are alarmingly low (<75 nmol/L) in 65-70% of North American children older than 1 year. An increased risk of viral upper respiratory tract infections (URTI), asthma-related hospitalizations and use of anti-inflammatory ...
Birken, Catherine S, Borkhoff, Cornelia M, Hoch, Jeffrey S, Loeb, Mark B, Macarthur, Colin, Maguire, Jonathon L, Mamdani, Muhammad, Mazzulli, Tony, Parkin, Patricia C, TARGet Kids! Collaboration, Thorpe, Kevin   +10 more
core   +3 more sources

Inhaled corticosteroids versus long-acting beta -agonists for chronic obstructive pulmonary disease (Review). [PDF]

, 2011
Long-acting beta(2)-agonists and inhaled corticosteroids can be used as maintenance therapy by patients with moderate to severe chronic obstructive pulmonary disease. These interventions are often taken together in a combination inhaler.
Agarwal, Anderson, Appleton, Barnes, Borgstrom, Borgstrom, Boyd, Burge, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverly, Campbell, Campell, Cazzola, Cazzola, Celli, Celli, Celli, Celli, Corhay, Dahl, Della Cioppa, Egede, Ferguson, Ferguson, Gosman, Greefhorst, Halpin, Halpin, Halpin, Hanania, Hanania, Hanania, Higgins, Horstman, Hunjan, Hunjan, Hunjan, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Keene, Korsgaard, Kristufek, Lange, Lofdahl, Lofdahl, Lofdahl, Lofdahl, Lyseng-Williamson, Mahler, Mahler, Mahler, McGarvey, Milanowski, Nannini, Nannini, Nannini Luis, Nitschmann, Pauwels, Pauwels, Reynolds, Rodrigo, Rodrigo, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Szafranski, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Yang   +105 more
core   +2 more sources

A study to assess COPD Symptom-based Management and to Optimise treatment Strategy in Japan (COSMOS-J) based on GOLD 2011 [PDF]

, 2013
Background and objective: The Global initiative for chronic Obstructive Lung Disease(GOLD) Committee has proposed a chronic obstructive pulmonary disease (COPD) assessment framework focused on symptoms and on exacerbation risk. This study will evaluate a
Betsuyaku, T, Fujimoto, K, Hagan, G, Hitosugi, H, James, M, Jones, PW, Kato, M, Kobayashi, A   +7 more
core   +1 more source

Acute exacerbation of COPD [PDF]

Respirology, 2016
AbstractThe literature of acute exacerbation of chronic obstructive pulmonary disease (COPD) is fast expanding. This review focuses on several aspects of acute exacerbation of COPD (AECOPD) including epidemiology, diagnosis and management. COPD poses a major health and economic burden in the Asia‐Pacific region, as it does worldwide. Triggering factors
Fanny W. Ko, Ka Pang Chan, David S. Hui, John R. Goddard, Janet G. Shaw, David W. Reid, Ian A. Yang   +6 more
openaire   +5 more sources

Inhaled corticosteriod use and the risk of pneumonia and COPD exacerbations in the UPLIFT study [PDF]

, 2017
Rationale Unlike many other COPD studies, the 4-year UPLIFT trial permitted inhaled corticosteroid (ICS) use during run-in and treatment phases. This provided the opportunity to prospectively observe the continuing effects of ICS on respiratory events in
Morice, Alyn, Morice, Alyn H., Morjaria, Jaymin, Morjaria, Jaymin B., Rigby, Alan   +4 more
core   +1 more source

Anemia Severely Reduces Health-Related Quality of Life in COPD Patients Receiving Long-Term Home Non-Invasive Ventilation

International Journal of COPD, 2021
Maximilian Wollsching-Strobel, Sarah Bettina Schwarz, Tim Mathes, Daniel Sebastian Majorski, Pouya Heidari, Doreen Kroppen, Friederike Sophie Magnet, Wolfram Windisch Cologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln gGmbH ...
Wollsching-Strobel M, Schwarz SB, Mathes T, Majorski DS, Heidari P, Kroppen D, Magnet FS, Windisch W   +7 more
doaj  

Comparative Effectiveness of Step-up Therapies in Children with Asthma Prescribed Inhaled Corticosteroids : A Historical Cohort Study [PDF]

, 2017
This work was supported by the Respiratory Effectiveness Group. Acknowledgments We thank the Respiratory Effectiveness Group for funding this work, Annie Burden for assistance with statistics, and Simon Van Rysewyk and Lisa Law for assistance with ...
Murray, Claire S., Price, David B., Richardson, Kathryn, Thomas, Mike, Turner, Steve W.   +4 more
core   +2 more sources

Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial. [PDF]

, 2015
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with high morbidity, mortality, and health-care costs. An incomplete response to the anti-inflammatory effects of inhaled corticosteroids is present in COPD.
Alyn Morice, Amanda J. Lee, Andrew Briggs, Andrew Wilson, Anita Sullivan, Anthony De Soyza, B Shah, BG Cosio, BG Cosio, BR Celli, CM Fletcher, David Price, E Stahl, G Cusack, GC Donaldson, GC Donaldson, Gladys McPherson, Graham Burns, Graham Devereux, H Chrystyn, H Chrystyn, H Chrystyn, H Chrystyn, Henry Chrystyn, JA Marwick, JC Bestall, JJ Soler-Cataluna, JK Quint, John Haughney, John Norrie, JR Hurst, JR Powell, JR Powell, JW Dodd, K Ito, K Ito, K Ito, K Ito, K Ohta, KC Farmer, Kirsty McCormack, KL Hattotuwa, L Hendeles, Lisa Davies, M Britton, M Ferrer, MC Cyr, MR Miller, P Dolan, P Sullivan, PA Ford, Peter Barnes, PJ Barnes, PJ Barnes, PW Jones, Rekha Chaudhuri, RG Barr, S Lim, Seonaidh Cotton, Shona Fielding, Simon Gompertz, SN Hunt, SV Culpitt, SV Culpitt, TA Seemungal, The EuroQol Group, WJ Jusko, WJ Jusko, Y To   +68 more
core   +4 more sources

Effect of fixed-dose subcutaneous reslizumab on asthma exacerbations in patients with severe uncontrolled asthma and corticosteroid sparing in patients with oral corticosteroid-dependent asthma : results from two phase 3, randomised, double-blind, placebo-controlled trials [PDF]

, 2020
BACKGROUND: Reslizumab 3 mg/kg administered intravenously is approved for the treatment of severe eosinophilic asthma. We assessed the safety and efficacy of subcutaneous reslizumab 110 mg in two trials in patients with uncontrolled severe asthma and ...
Adir, Yochai, Bernstein, Jonathan A, Brusselle, Guy, Castro, Mario, Garin, Margaret, Hickey, Lisa, Humbert, Marc, Jacobs, Joshua, Marsteller, Douglas A, Maspero, Jorge Fernando, McElhattan, Jennifer, Murphy, Kevin, Vanlandingham, Rebecca, Virchow, J Christian   +13 more
core   +1 more source

Plasma Extracellular Vesicle miRNA Profiles Distinguish Chronic Obstructive Pulmonary Disease Exacerbations and Disease Severity

International Journal of COPD, 2022
Hannah E O’Farrell, Rayleen V Bowman, Kwun M Fong, Ian A Yang Faculty of Medicine, the University of Queensland, Brisbane, QLD, AustraliaCorrespondence: Hannah E O’Farrell, Faculty of Medicine, the University of Queensland, Brisbane, QLD, Australia, Tel +
O'Farrell HE, Bowman RV, Fong KM, Yang IA   +3 more
doaj