Results 31 to 40 of about 140,049 (297)
, 2008 COPD (Chronic Obstructive Pulmonary Disease) worldwide has a prevalence of10% in men and 8.5% in women. Exacerbations of COPD account forapproximately 10% of all acute medical admissions.
Bourne, Simon Charles
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Journal of Asthma and Allergy, 2021 David Price,1,2 Andrew Menzies-Gow,3 Claus Bachert,4 Giorgio Walter Canonica,5 Janwillem Kocks,1 Asif H Khan,6 Fen Ye,7 Paul J Rowe,7 Yufang Lu,8 Siddhesh Kamat,8 Victoria Carter,1 Jaco Voorham1,9 1Observational and Pragmatic Research Institute (OPRI ...
Price D +11 more
doaj
Lung function, symptoms and inflammation during exacerbations of non-cystic fibrosis bronchiectasis: a prospective observational cohort study. [PDF]
, 2015 Exacerbations of non-cystic fibrosis bronchiectasis cause significant morbidity but there are few detailed data on their clinical course and associated physiological changes.
Hurst, JR +5 more
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
International Journal of COPD, 2016 Xuehua Ke,1 Jessica Marvel,2 Tzy-Chyi Yu,2 Debra Wertz,1 Caroline Geremakis,1 Liya Wang,1 Judith J Stephenson,1 David M Mannino3 1HealthCore Inc., Wilmington, DE, 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, 3University of Kentucky ...
Ke X +7 more
doaj
Winds of change a tale of: asthma and microbiome
Frontiers in Microbiology, 2023 The role of the microbiome in asthma is highlighted, considering its influence on immune responses and its connection to alterations in asthmatic patients.
David Galeana-Cadena +17 more
doaj +1 more source
American Journal of Respiratory and Critical Care Medicine, 2018 Asthma is a very common disease in adults, including in those who work outside the home. Work-related asthma refers to asthma that is either caused by or worsened by something at work. It is very important to know whether someone has work-related asthma because there are specific ways to manage it.
openaire +2 more sources
Asthma outcomes: Exacerbations [PDF]
Journal of Allergy and Clinical Immunology, 2012 The goals of asthma treatment include preventing recurrent exacerbations. Yet there is no consensus about the terminology for describing or defining “exacerbation,” or about how to characterize an episode’s severity.
Anne, Fuhlbrigge +10 more
openaire +2 more sources