Results 81 to 90 of about 140,049 (297)

An Anti-Human ICAM-1 Antibody Inhibits Rhinovirus-Induced Exacerbations of Lung Inflammation [PDF]

open access: yes, 2013
15.04.14 KB.
Johnston Sebastian L.   +109 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Diaphragmatic Movement at Rest and After Exertion: A Non-Invasive and Easy to Obtain Prognostic Marker in COPD

open access: yesInternational Journal of COPD, 2022
Evgeni Mekov,1 Nikolay Yanev,2 Nedelina Kurtelova,2 Teodora Mihalova,2 Adelina Tsakova,3 Yordanka Yamakova,4 Marc Miravitlles,5 Rosen Petkov2 1Department of Occupational Diseases, Medical University Sofia, Sofia, Bulgaria; 2Department of Pulmonary ...
Mekov E   +7 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Acute exacerbations of COPD

open access: yesSwiss Medical Weekly, 2003
Acute exacerbations of COPD (AECOPD) are a common cause of morbidity and mortality. There is a need for a standardised definition of an exacerbation of COPD. The common aetiological factors are bacterial, viral infection and air pollutants. Exacerbations of COPD may adversely affect the natural history of COPD.
openaire   +3 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Spirometry, the St. George’s Respiratory Questionnaire, and other clinical measures as predictors of medical costs and COPD exacerbation events in a prospective cohort

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2015
Purpose:We conducted a prospective clinical cohort study of 300 established COPD patients randomly recruited from one managed care system to examine how well a battery of spirometry, exercise, and health status measures, including the St.
Douglas W Mapel, Melissa Roberts
doaj  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

FENOMA Study: Achieving Full Control in Patients with Severe Allergic Asthma

open access: yesJournal of Asthma and Allergy, 2020
Sheila Cabrejos,1 Ana Moreira,2 Andreina Ramirez,2 Santiago Quirce,3 Gregorio Soto Campos,4 Ignacio Dávila,5 Paloma Campo6 1Allergy Service, Hospital Rafael Mendez de Lorca, Murcia, Spain; 2Novartis Farmacéutica, Barcelona, Spain ...
Cabrejos S   +6 more
doaj  

COPD Exacerbations, Costs, and Health Care Resource Utilization Before and After Initiation of Fluticasone Furoate/Umeclidinium/Vilanterol in Routine Care in the USA

open access: yesInternational Journal of COPD, 2023
Nicola A Hanania,1 Scott H Bunner,2 Lindsay GS Bengtson,2 Afisi S Ismaila,3,4 Michael Bogart5 1Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, USA; 2Optum, Eden Prairie, MN, USA; 3Value Evidence and Outcomes, GSK,
Hanania NA   +4 more
doaj  

Home - About - Disclaimer - Privacy