Results 101 to 110 of about 1,376,473 (288)

Internal exact controllability of the linear population dynamics with diffusion

open access: yesElectronic Journal of Differential Equations, 2004
We consider the internal exact controllability of a linear age and space structured population model with nonlocal birth process. The control acts only in a spatial subdomain and only for small age classes.
Bedr'Eddine Ainseba, Sebastian Anita
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Null controllability of a nonlinear heat equation

open access: yesAbstract and Applied Analysis, 2002
We study the internal exact null controllability of a nonlinear heat equation with homogeneous Dirichlet boundary condition. The method used combines the Kakutani fixed-point theorem and the Carleman estimates for the backward adjoint linearized system ...
G. Aniculăesei, S. Aniţa
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Exact Estimates for Moments of Random Bilinear Forms

open access: yesJournal of Theoretical Probability, 2001
28 pages; To be published in the Journal of Theoretical Probability; minor changes have been ...
Ibragimov, R.   +2 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Large Igneous Province thermogenic greenhouse gas flux could have initiated Paleocene-Eocene Thermal Maximum climate change

open access: yesNature Communications, 2019
The Paleocene-Eocene Thermal Maximum constitutes one of the largest climate perturbations in Earth’s history, but its exact causes are not well known.
Stephen M. Jones   +3 more
doaj   +1 more source

Accounting estimates in financial statements and their disclosure by some South African construction companies

open access: yesJournal of Economic and Financial Sciences, 2013
Accounting estimates form part of the preparation of financial statements and should not affect faithful representation. The use of accounting estimates does not yield exact amounts, but, rather, amounts based on assumptions.
Elsje Raubenheimer
doaj   +1 more source

Exact Fiducial Limits in Non-Linear Estimation

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1962
SUMMARY In the problem of estimating an unknown parameter of a distribution (in normal regression or in more general situations), the determination of a point estimate and its distribution is contrasted with the setting of fiducial limits for the parameter value.
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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