Results 71 to 80 of about 347,458 (339)

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Vlog to Death: Project Eliseg's Video-Blogging

Internet Archaeology, 2015
Project Eliseg involved three field seasons (2010–12) of survey and excavation at the multi-period mortuary and commemorative monument known as the Pillar of Eliseg, near Llangollen, Denbighshire, Wales.
Joseph Tong, Suzanne Evans, Howard Williams, Nancy Edwards, Gary Robinson   +4 more
doaj   +1 more source

Investigation of Lateral Stress Relief on theStability of PHI = 0 DEG Slopes Using Laboratory, Fracture Mechanics, and Finite Element Method Approaches [PDF]

, 2011
Total stress analyses of purely cohesive cut slopes utilize the undrained shear strength for slope stability analyses. These slopes can have an in-situ lateral earth pressure that is greater than the vertical pressure.
Kutschke, Walter
core  

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Classical Landscape - Rural Archaeology At Metaponto [PDF]

, 1980
Anthropolog
Carter, Joseph Coleman
core   +1 more source

REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy

Advanced Science, EarlyView.
REEP1 contributes to endoplasmic reticulum (ER) shaping. Variants either cause cortical motoneuron degeneration and hereditary spastic paraplegia (HSP) or spinal motoneuron degeneration and distal hereditary motor neuropathy (dHMN). Knockout causes less complex ER structures and cortical motoneuron loss.
Andrea Bock, Mona Schurig, Miles Willoughby, Andrea Mirecki, Eric Seemann, Kateryna Lohachova, Istvan Katona, Sonnhild Mittag, Lutz Liebmann, Patricia Franzka, Mehdi Heidari Horestani, Mukhran Khundadze, Thorsten Mosler, Timothy Louie, Marianne de Visser, Marian A. J. Weterman, Michael Kiehntopf, Christian Beetz, Sandor Nietzsche, Otmar Huber, Joachim Weis, Michael M. Kessels, Ramachandra M. Bhaskara, Britta Qualmann, Ivan Đikić, Christian A. Hübner   +25 more
wiley   +1 more source

Justification of efficient options of fully-mechanized extraction of pitch coal at Kuang Khan Mine

Горные науки и технологии, 2016
Currently, the Vinacomin company actively mechanizes coal mining processes, developing process solutions for coal mining in complicated geological conditions.
N. I. Abramkin, Duc Thang Pham
doaj   +1 more source

Gregory McMahon Associate Professor of History, COLA, travels to Turkey [PDF]

, 2011
Every summer since 1993, Professor McMahon has travelled to central Turkey to conduct a research project at the Çadır Höyük Excavation site.
McMahon, Gregory
core   +2 more sources

Modulating a Massive Set of Biomolecular Structures by Sono‐Mechanical Force

Advanced Science, EarlyView.
Using low‐power ultrasound exposure, picoNewton forces are generated to release loaded drugs after unfolding secondary structures in DNA nanoassemblies. This opens a door to reversibly manipulate a large set of biomolecular structures both inside and outside cells without the damages incurred by high‐power sonications currently used in the field ...
Pravin Pokhrel, Grinsun Sharma, Jaren Jenyk, Alyssa Lower, Jiahao Ji, Sajan Shakya, Joseph Haun, Hanbin Mao   +7 more
wiley   +1 more source