Results 51 to 60 of about 183,413 (314)
Polymer ejection from strong spherical confinement
, 2015 We examine the ejection of an initially strongly confined flexible polymer from a spherical capsid through a nanoscale pore. We use molecular dynamics for unprecedentedly high initial monomer densities.
Linna, R. P., Piili, J.
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Propagation and deposition of stony debris flows at channel confluences [PDF]
, 2015 The fluid dynamics of stony debris flows generated in two small tributaries adjacent to each other and flowing into a main receiving channel was analyzed experimentally at a laboratory scale.
Foti, E. +2 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Catalogue of analytical solutions for consolidation of unsaturated soils subjected to various initial conditions and time-dependent loadings [PDF]
, 2016 University of Technology Sydney. Faculty of Engineering and Information Technology.Soil consolidation has been a primary geotechnical interest for decades.
Ho, Huu Liem
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Effects of Excess Pore Pressure Redistribution in Liquefiable Layers
Journal of Geotechnical and Geoenvironmental EngineeringExisting simplified procedures for evaluating soil liquefaction potential or for estimating excess pore pressures during earthquakes are typically based on undrained cyclic tests performed on saturated soil samples under controlled loading and boundary conditions.
Sumeet K. Sinha +2 more
openaire +3 more sources
Liquefaction of Highly Saturated Sand Layer under Oscillating Water Pressure [PDF]
, 1982 In this paper the vertical distribution of pore water pressure in the highly saturated sand layer under the oscillating water pressure are treated theoretically and experimentally. By the experiments it is shown that the water pressure acting on the sand
Nago, Hiroshi
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Stabilized material point methods for coupled large deformation and fluid flow in porous materials
, 2019 The material point method (MPM) has been increasingly used for the simulation of large deformation processes in fluid-infiltrated porous materials. For undrained poromechanical problems, however, standard MPMs are numerically unstable because they use ...
Choo, Jinhyun, Zhao, Yidong
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