Results 1 to 10 of about 76,164 (271)

A fluorescence sensor for nitroreductase detection in hypoxic cells and zebrafish

Results in Chemistry, 2021
Nitroreductase (NTR) is a type of cytoplasmic enzyme that depends on flavin mononucleotide or flavin adenine dinucleotide, and that is widely present in tumor cells where it increases during hypoxia. NTR can effectively reduce aromatic nitro compounds to
Wan Sun, Mingqiong Tong, Guofeng Liu, Xiaoyue Wang, Na Fan, Xinfeng Song, Dongying Yang, Di Zhang   +7 more
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Decreased Penetration Mechanism of Ranitidine Due to Application of Sodium Sulfobutyl Ether-β-Cyclodextrin

Pharmaceutics, 2023
Permeability has an important effect on drug absorption. In this study, the effect of different concentrations of sodium sulfobutyl ether-β-cyclodextrin (SBE-β-CD) on the absorption of ranitidine was investigated to examine the mechanism of permeability ...
Rui Yang, Jing Zhang, Jiaqi Huang, Xiaofeng Wang, Huiying Yang, Qingri Jin   +5 more
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Liposomal remdesivir inhalation solution for targeted lung delivery as a novel therapeutic approach for COVID-19

Asian Journal of Pharmaceutical Sciences, 2021
Strong infectivity enables coronavirus disease 2019 (COVID-19) to rage throughout the world. Moreover, the lack of drugs with definite therapeutic effects further aggravates the spread of the pandemic.
Jingjing Li, Kai Zhang, Di Wu, Lianjie Ren, Xinyu Chu, Chao Qin, Xiaopeng Han, Taijun Hang, Yungen Xu, Lei Yang, Lifang Yin   +10 more
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Reversing the PAI-1-induced fibrotic immune exclusion of solid tumor by multivalent CXCR4 antagonistic nano-permeator

Acta Pharmaceutica Sinica B, 2023
Fibrosis is one of the key factors that lead to the immune exclusion of solid tumors. Although degradation of fiber is a promising strategy, its application was still bottlenecked by the side effects of causing metastasis, resulting in the failure of ...
Jingwen Dong, Chenfei Zhu, Ying Huang, Quanhao Li, Jing Li, Zheng Wang, Yixin Wang, Zhanwei Zhou, Minjie Sun   +8 more
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Application of text-mining techniques for extraction and analysis of paracetamol and ibuprofen marketed products' qualitative composition [PDF]

Arhiv za farmaciju, 2022
Text mining (TM) applications in the field of biomedicine are gaining great interest. TM tools can facilitate formulation development by analyzing textual information from patent databases, scientific articles, summary of products characteristics, etc ...
Đuriš Jelena, Pilović Jovana, Džunić Marina, Cvijić Sandra, Ibrić Svetlana   +4 more
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Crystal structure of (1,10-phenanthroline-κ2N,N′)-bis(3-thiophenecarboxylato-κ2O,O′)copper(II), C22H14N2O4S2Cu

Zeitschrift für Kristallographie - New Crystal Structures, 2021
C22H14N2O4S2Cu, orthorhombic, Pbcn (no. 60), a = 20.171(7) Å, b = 9.684(3) Å, c = 10.372(4) Å, V = 2025.9(12) Å3, Z = 4, Rgt(F) = 0.0334, wRref(F2) = 0.0908, T = 273.15 K.
Zhang Zhongyu, Men Xiaoxia, Han Bing, Sun Chunyan   +3 more
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A polyoxyethylene sorbitan oleate modified hollow gold nanoparticle system to escape macrophage phagocytosis designed for triple combination lung cancer therapy via LDL-R mediated endocytosis

Drug Delivery, 2020
Presently, a combination of chemotherapy, radiotherapy, thermotherapy, and other treatments has become a hot topic of research for the treatment of cancer, especially lung cancer.
Yan Shen, Yun Xia, Ershuang Yang, Zixuan Ye, Yuan Ding, Jiasheng Tu, Yong Zhang, Pengcheng Xu   +7 more
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Enhanced cytotoxicity of a redox-sensitive hyaluronic acid-based nanomedicine toward different oncocytes via various internalization mechanisms

Drug Delivery, 2020
Receptor-mediated active targeting and tumor microenvironment responsive systems from polymeric micelles have been studied for rapid cellular internalization and triggered drug release.
Yunai Du, Sheng Wang, Tianhao Zhang, Dongsheng He, Jiasheng Tu, Yan Shen   +5 more
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Syntheses, crystal structure, thermal behavior, and anti-tumor activity of three ternary metal complexes with 2-chloro-5-nitrobenzoic acid and heterocyclic compounds

Heterocyclic Communications, 2022
Three complexes, namely complex (1), complex (2), and complex (3), were synthesized and characterized by X-ray diffraction, thermogravimetric study, and elemental study.
Zhang Zhongyu, Chen Meng, Tong Mingqiong, Sun Wan, Dong Pingxuan, Song Xinfeng, Wang Xiaoyue   +6 more
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The crystal structure of aqua-bis(6-chloropicolinato-κ2N,O)copper(II), C12H8Cl2N2O5Cu

Zeitschrift für Kristallographie - New Crystal Structures, 2021
C12H8Cl2N2O5Cu, triclinic, P1‾$P‾{1}$ (no. 2), a = 6.800(2) Å, b = 9.086(3) Å, c = 11.363(4) Å, α = 86.701(6)°, β = 84.830(5)°, γ = 77.353(5)°, V = 681.7(4) Å3, Z = 2, Rgt(F) = 0.0250, wRref(F2) = 0.0655, T = 296(2) K.
Zhang Zhongyu, Tong Mingqiong, Liu Yanling   +2 more
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