Results 171 to 180 of about 76,164 (271)

Beyond Side Effect: Immuno-Ethical Risk Analysis of Animal-Derived Ingredients in Pharmaceuticals. [PDF]

Risk Manag Healthc Policy
Herdiana Y, Gozali D, Putriana NA, Muchtaridi M, Shamsuddin S, Sofian FF.   +5 more
europepmc   +1 more source

Repeated injection of pooled frozen allogeneic umbilical cord blood mesenchymal stromal cells in 5 flat‐racing horses

Equine Veterinary Education, Volume 38, Issue 4, Page 183-194, April 2026.
Summary Background Tendinopathies in racehorses are challenging to treat, and restoring normal tendon composition remains elusive despite extensive research. Equine multipotent mesenchymal stromal cells (MSC) have shown promise for tendon repair, and various sources of MSC have been described.
A. Merchan Muñoz, N. Coté, T. Koch, S. Mehrpouyan, A. H. Alizadeh, K. A. Russell, G. Monteith, J. Koenig   +7 more
wiley   +1 more source

Immunological Considerations of Polysorbate as an Excipient in Botulinum Neurotoxin Type A Formulations: A Narrative Review. [PDF]

Toxins (Basel)
Martin MU, Frevert J, Park JY, Cui H, Curry A, Loh WQ.   +5 more
europepmc   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, Volume 15, Issue 10, 13 March 2026.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Short Peptides as Excipients in Parenteral Protein Formulations: A Mini Review. [PDF]

Pharmaceutics
Migoń D, Jaremicz Z, Kamysz W.
europepmc   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Machine learning driven acceleration of biopharmaceutical formulation development using Excipient Prediction Software (ExPreSo). [PDF]

Comput Struct Biotechnol J
Vidal-Henriquez E, Holder T, Lee NF, Pompe C, Teese MG.   +4 more
europepmc   +1 more source

Purity profiling of peptide drugs [PDF]

, 2011
De Spiegeleer, Bart, Van Dorpe, Sylvia, Verbeken, Mathieu, Wynendaele, Evelien   +3 more
core   +1 more source

Machine Learning‐Informed Nano Co‐Assembly Inhibits Fibroblast Activation Protein and Improves Drug Delivery in Fibrotic Tissue

Advanced Materials, Volume 38, Issue 17, 20 March 2026.
We present SP‐13786 (SP), a fibroblast activation protein (FAP) inhibitor, as a universal excipient for co‐assembling stable drug nanoparticles (SCAN). Assembly mechanism deciphered by molecular dynamics and explainable machine learning, SCAN attenuate fibrosis‐induced stromal barriers, enhances lesional drug accumulation, and improves therapeutic ...
Zehua Liu, Qiang Long, Yihao Liu, Xiuqiao Sun, Baoding Zhang, Binxin Liao, Weibin Wu, Wangxi Hai, Pei Zhang, Wenhua Lian, Yuewen Zhu, Zheng Wang, Caisheng Wu, Xianming Deng, Hélder A. Santos, Xiaofeng Ye   +15 more
wiley   +1 more source

Drug Excipients. Necessary but Not Harmless.

Farm Comunitarios
Baixauli-Fernández VJ.
europepmc   +1 more source