Results 191 to 200 of about 53,055 (281)

Clinically relevant intra‐articular corticosteroid doses impair equine osteoclast function in vitro

Veterinary Surgery, EarlyView.
Abstract Objective To assess the effects of clinically relevant doses of commonly employed intra‐articular corticosteroids—specifically, triamcinolone acetonide (TCA), methylprednisolone acetate (MPA), and combination of betamethasone acetate and betamethasone sodium phosphate (BM)—on equine osteoclasts.
Gwladys Malek, Louis Kamus, Hélène Richard, Guy Beauchamp, Sheila Laverty   +4 more
wiley   +1 more source

Influence of Excipients on the Release Kinetics and Antioxidant Activity of Encapsulated Propolis Phenolic Compounds. [PDF]

Antioxidants (Basel)
Jokubaite M, Marksa M, Nefodov O, Sakharova T, Ramanauskiene K.   +4 more
europepmc   +1 more source

Design‐Assisted Chemometric UV Spectrophotometric Determination of Candesartan Cilexetil, Chlorthalidone and Amlodipine Using Principal Component Regression, Partial Least Squares and Genetic Algorithm‐Partial Least Squares Models

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT This study presents a sustainable chemometric‐assisted UV spectrophotometric strategy for the simultaneous determination of candesartan cilexetil (CAN), chlorthalidone (CTL) and amlodipine (AML) in laboratory‐prepared mixtures and commercial pharmaceutical formulations.
Khanda F. M. Amin, Samar H. Elagamy, Reem H. Obaydo, Hayam M. Lotfy   +3 more
wiley   +1 more source

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper. [PDF]

Allergy
Garvey LH, Brockow K, Barbaud A, Mortz CG, Calogiuri G, Gelincik A, Yeğit OO, Nakonechna A, Wagner A, Schrijvers R, Ieven T.   +10 more
europepmc   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1120-1128, October 2026.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow, Brendan Day, Esther H. Zhou, Corinne Woods, Nana Dwumfour, Jenni Y. Lee, Ilynn Bulatao, Sanae Cherkaoui, Manish Kalaria, Sonja Brajovic, Nabila Sadiq, Farideh Sistani, Maggie Lee, Grace Chai, Gerald Dal Pan   +14 more
wiley   +1 more source

Label-free quantification of topical drug permeation in skin using sparse spectral sampling stimulated Raman scattering imaging. [PDF]

Biophotonics Discov
Tu D, Riseman J, Wei Y, Ghosh P, Raney SG, Luke MC, Evans CL.   +6 more
europepmc   +1 more source

Formulation‐Dependent Cytotoxic Effects of Commercial and Analytical‐Grade Mancozeb in C6 Glial Cells

Journal of Applied Toxicology, Volume 46, Issue 10, Page 3542-3549, October 2026.
ABSTRACT Mancozeb (MZ) is a widely used dithiocarbamate fungicide composed of manganese (Mn) and zinc (Zn) complexes. Increasing concern has been raised regarding its occupational and human health relevance, particularly due to its neurotoxic potential associated with Mn‐related cellular dysfunction.
Lavínia Lazzarotti, Felipe Vanz, Karina Giacomini Varela, Viviane Glaser, Diego de Carvalho, Aline Pertile Remor   +5 more
wiley   +1 more source

Texture Analyzer-Derived SeDeM-ODT Extension for Bisoprolol Fumarate Orodispersible Tablets: Formulation Discrimination Within a Pharmacopoeial Disintegration-Compliant Space. [PDF]

Pharmaceutics
Afşin Ç, Şahbaz S, Özer-Önder S, Uğurlu T.   +3 more
europepmc   +1 more source

Nanoemulsification Promotes Antibacterial Activity of Selected Essential Oils Against Multidrug‐Resistant Staphylococcus aureus Biofilms In Vitro

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Schematic illustration of the workflow for the fabrication and biological evaluation of essential oil (EO)–based nanoemulsions (NEs). The NEs exhibited superior antibacterial activity compared with the corresponding crude EOs while maintaining high biosafety toward a skin cell line. ABSTRACT Essential oils (EOs) are unique materials with healing powers
Sumeena Karki, Mahnaz Ramezanpour, Clare M. Cooksley, Emma Barry, Clive A. Prestidge, Roshan Nepal, Sholeh Feizi, Dianne Correll, Peter‐John Wormald, Sarah Vreugde, Muhammed Awad   +10 more
wiley   +1 more source

Simple Hydrodynamic Molecular Weight Model for Rapid Assessment of Therapeutic Protein Oligomerization States in Formulation. [PDF]

AAPS J
Lu J, Chen K.
europepmc   +1 more source