Results 171 to 180 of about 33,580 (237)

Expiration Date of Extemporaneous Pyrimethamine Formulations for Treating Congenital Toxoplasmosis: Physicochemical and Microbiological Evaluation. [PDF]

ACS Omega
de Paula RM, Santana VBS, Amorim MVP, Dourado D, Alencar ÉDN, de Aquino DAO, Veríssimo LM.   +6 more
europepmc   +1 more source

Open‐Label, Balanced, Randomized, Single‐Dose, Three‐Treatment, Three‐Sequence, Three‐Period, Three‐Way Crossover Oral Bioequivalence Study of Desmopressin Acetate Oral Solution

Clinical Pharmacology in Drug Development, Volume 15, Issue 8, August 2026.
ABSTRACT Desmopressin is first‐line therapy for central diabetes insipidus, also known as arginine vasopressin deficiency, but presents dosing challenges due to its narrow therapeutic index. This open‐label, randomized, three‐way crossover study evaluated the bioequivalence of a new desmopressin acetate oral solution (50 mcg/mL) compared to ...
Adam Christensen, Axay Parth, Mansi Kotak, Danka Radosavjevic, Catherine Gorman Moore, Byung‐Woun Seo   +5 more
wiley   +1 more source

Eco-friendly approach for spectrofluorimetric determination of moxifloxacin in pharmaceutical formulations and biological samples using deep eutectic solvents. [PDF]

BMC Chem
Muhammad SS, Karim WO, Al-Dulaimi N.
europepmc   +1 more source

The Effects of Bromelain Supplementation on Clinical Outcomes, Inflammatory and Oxidative Stress Biomarkers in Patients With Traumatic Brain Injury: A Randomized, Double‐Blind Placebo‐Controlled Clinical Trial

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Bromelain supplementation significantly reduced IL‐6 levels (p < 0.001), APACHE scores (p = 0.011), SOFA scores (p < 0.001), and NUTRIC scores (p < 0.001). Furthermore, 60‐day mortality was significantly lower in the Bromelain group compared to the Placebo group (p = 0.036). However, there was no significant effect on CRP (p = 0.377) or MDA levels (p = 
Alireza Gheflati, Mohammad Rashid Mayvan, Mojgan Mehri Ardestani, Seyed Mahdi Mirghazanfari, Ebrahim Hazrati, Mohamad Shahab Kalantar, Vahid Hadi, Ali Jafarzadeh Esfehani, Saeid Hadi   +8 more
wiley   +1 more source

Optimization of Sugar-Derivatives Mixtures for Stabilizing Polyclonal Immunoglobulin G in Spray-Dried Inhalable Powders During Processing and Long-Term Storage. [PDF]

Pharmaceutics
Gevenois P, Bui LV, Sebti T, Heyden YV, Amighi K, Wauthoz N.   +5 more
europepmc   +1 more source

The Role of Research, Quality Improvement, and Training in Achieving Medicines Security in Nigeria: A Cross‐Sectional Exploration of Stakeholders' Perspectives

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Equitable access to medicines remains a challenge in Nigeria with issues such as sub‐optimal national pharmaceutical production capacities and the need to improve relevant quality standards. Thus, in order to identify context‐specific solutions to this challenge, this study aimed to assess the perspectives of stakeholders ...
Obi Peter Adigwe, Godspower Onavbavba, Toluwalope Folashade Alabi, Nwakaego Rosemary Uzuh   +3 more
wiley   +1 more source

Differentiating Resistance from Formulation Failure: Isoniazid Instability and Poor Dissolution in Crushed Multi-Drug Paediatric Preparations. [PDF]

Pharmaceutics
Samsodien H, Winkler J, Aucamp M, Garcia-Prats AJ.   +3 more
europepmc   +1 more source

Differentiation of Plant and Animal‐Derived Cholesterol Using irm‐13C NMR and IRMS

Magnetic Resonance in Chemistry, Volume 64, Issue 8, Page 701-708, August 2026.
Determining and certifying the origin of ingredients, starting materials, and excipients used in manufactured goods like cosmetics and medicines can be difficult. In this report, we describe a robust approach for identifying the origin of cholesterol, a component of myriad consumer products using irm‐13C NMR and IRMS to differentiate plant versus ...
Anika M. Singh, Subir Chakraborty, Remington X. Poulin, R. Thomas Williamson   +3 more
wiley   +1 more source

Wood Hemicellulose-Based Spray-Dried Microencapsulation of a Lytic Bacteriophage Preserves Phage Viability and Improves Control of the Bacterial Wilt Pathogen Ralstonia solanacearum. [PDF]

Microb Biotechnol
Negroni AM, Hendrich CG, Ho MT, Yousefvand A, Friman VP.   +4 more
europepmc   +1 more source

Ultrasmall Cyclodextrin‐Based Nanogels as Drug Delivery Systems

ChemistryOpen, Volume 15, Issue 8, August 2026.
Cyclodextrin (CD) nanogels provide a highly effective, biocompatible platform for advanced drug delivery. These specialized networks successfully encapsulate active ingredients, significantly improving overall drug solubility. Furthermore, the resulting nanogels exhibit enhanced toxicity toward cancer cell lines compared to the parent CDs.
Andrea Cesari, Simona Braccini, Maria Antonietta Casulli, Kento Ishigaki, Takeshi Hashimoto, Takashi Hayashita, Dario Puppi, Fabio Bellina   +7 more
wiley   +1 more source