Results 171 to 180 of about 77,170 (289)

A Novel Ultra‐Performance Liquid Chromatography‐Electrospray Ionisation‐Tandem Mass Spectrometry Method for Quantification of Imeglimin in Human Plasma: Application to a Bioequivalence Study

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT The pharmaceutical market has recently witnessed the advent of a novel tetrahydrotriazene molecule belonging to the new pharmacological class “Glimins”, named Imeglimin (IMG). It has been approved in Japan as a safe and highly effective oral diabetic drug for type II diabetic patients.
Mina Wadie, Kamal A. Badr, Ahmed A. Hosny, Liliya Logoyda, Omnia M. El Sebai, Mamdouh R. Rezk   +5 more
wiley   +1 more source

Investigation on a Freeze-Drying Process for Long-Term Stability of mRNA-LNPs. [PDF]

Vaccines (Basel)
Khan MDFH, Sudalaiyadum Perumal A, Kamen AA.   +2 more
europepmc   +1 more source

Development and Optimization of a Nanophytosomes‐Based Thermogel as a Topical Anti‐Psoriatic for Increased Solubility and Bioavailability

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Schematic illustration of the development, optimization, and therapeutic evaluation of the Leucas aspera phytosome‐based thermogel for topical antipsoriatic therapy, highlighting its enhanced solubility, skin deposition, and in vivo efficacy in an imiquimod‐induced psoriasis model. Created with BioRender.com.
Ananda Kumar Chettupalli, Thatipally Rajeshwar, Sarad Pawar Naik Bukke   +2 more
wiley   +1 more source

Contemporary Techniques and Prospects in Pharmaceutical Tablet Surface Analysis. [PDF]

ACS Meas Sci Au
Finšgar M.
europepmc   +1 more source

A Framework for Emergency Department–Integrated Hepatitis C Test‐and‐Treat in the United States

Journal of Viral Hepatitis, Volume 33, Issue 6, June 2026.
ABSTRACT Despite the availability of curative, direct‐acting antiviral therapy, hepatitis C virus elimination remains incomplete. Losses across the care cascade continue to limit impact, from initial diagnosis to sustained virologic response. Fewer than 1/3 of individuals ultimately achieve cure. These gaps reflect a delivery system that does not align
Saeed S. Graham
wiley   +1 more source

Differentiating Resistance from Formulation Failure: Isoniazid Instability and Poor Dissolution in Crushed Multi-Drug Paediatric Preparations. [PDF]

Pharmaceutics
Samsodien H, Winkler J, Aucamp M, Garcia-Prats AJ.   +3 more
europepmc   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Wood Hemicellulose-Based Spray-Dried Microencapsulation of a Lytic Bacteriophage Preserves Phage Viability and Improves Control of the Bacterial Wilt Pathogen Ralstonia solanacearum. [PDF]

Microb Biotechnol
Negroni AM, Hendrich CG, Ho MT, Yousefvand A, Friman VP.   +4 more
europepmc   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Drug Excipients. Necessary but Not Harmless.

Farm Comunitarios
Baixauli-Fernández VJ.
europepmc   +1 more source