Results 11 to 20 of about 76,164 (271)

“Petal-like” size-tunable gold wrapped immunoliposome to enhance tumor deep penetration for multimodal guided two-step strategy

Journal of Nanobiotechnology, 2021
Background Breast cancer is the fastest-growing cancer among females and the second leading cause of female death. At present, targeted antibodies combined with hyperthermia locally in tumor has been identified as a potential combination therapy to ...
Yanan Li, Wenting Song, Yumin Hu, Yun Xia, Zhen Li, Yang Lu, Yan Shen   +6 more
doaj   +1 more source

Transdermal evaluation of caffeine in different formulations and excipients [PDF]

, 2013
Background: The stratum corneum(SC) forms adifficultphysical barrier fordrugs to pass through the skin. Several strategieswere developed to overcome this barrier.Optimization of topical drug formulations by selected excipients may facilitate the ...
Boonen, Jente, Burvenich, Christian, De Spiegeleer, Bart, Mehuys, Els, Peremans, Kathelijne, Remon, Jean Paul, Roche, Nathalie, Veryser, Lieselotte   +7 more
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Selection Of A Filler For Tablets Manufactured With Direct Compression Method Containing Dry Ginger Extract [PDF]

, 2019
The preliminary studies of physico-chemical and pharmaco-technological properties of the dry extract of ginger have determined the need for introduction of different groups of excipients for developing a solid dosage form for the treatment of type II ...
Alkhalaf, M. (Malek), Gerbina, N. (Nataliia), Ruban, О. (Оlena)   +2 more
core   +3 more sources

Solubility improvement of progesterone from solid dispersions prepared by solvent evaporation and co-milling [PDF]

, 2020
The aim of this contribution was to evaluate the impact of processing methods and polymeric carriers on the physicochemical properties of solid dispersions of the poorly soluble drug progesterone (PG). Five polymers: hydroxypropyl methylcellulose (HPMC),
Al-Obaidi, Hisham, Chen, Xing, Nikolakakis, Ioannis, Partheniadis, Ioannis   +3 more
core   +1 more source

Influence of excipients on spray-dried powders for inhalation [PDF]

, 2014
Two areas attracting considerable attention when developing effective pulmonary drug delivery systems include the improvement of aerosolisation efficiency of the inhaled formulation and the controlled release of drug from the formulation following ...
Adi, Azarmi, Begat, Chan, Chew, Chew, Conti, Corrigan, Coucke, Derom, Edwards, Ely, En-Yu Xu, Farid, Glover, Gray, Griesenbach, Hao-Ying Li, Hooton, Jalalipour, Jing Guo, Kamiya, Kobayashi, Learoyd, Learoyd, Li, Li, Li, Li, Li, Mishra, Momeni, Parsons, Patton, Peter C. Seville, Prakash Rao, Seville, Seville, Sham, Sinn, Sou, Sou, Ståhl, Vergote, Ying Xu, Zeng   +45 more
core   +1 more source

Using small-angle X-ray scattering to investigate the compaction behaviour of a granulated clay [PDF]

, 2015
The compaction behaviour of a commercial granulated clay (magnesium aluminium smectite, gMgSm) was investigated using macroscopic pressure-density measurements, X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray microtomography (XμT) and ...
Aguzzi, Asare-Addo, Aulton, Baille, Barbara R. Conway, Baruchel, Beckett, Berisso, Briscoe, Busignies, Chipera, Djemai, Enes Šupuk, Feigin, Francis Sweeney, German, Hammond, Han, Ito, Kandeil, Kim, Kofi Asare-Addo, Kuklíc, Laity, Laity, Laity, Laity, Laity, Laity, Laity, Liddiard, Macleod, Mc.Donald, Mondol, Morel, Moyano, Murray, Nebgen, Oh, Peter R. Laity, Pizette, Pongjanyakul, Prakash, Rahaman, Roe, Romero, Schmidt, Sinka, Sinka, Sorensen, Stock, Sun, Tien, Train, Vanorio, Villamizar, Villar, Villar, Wu, Ye   +59 more
core   +1 more source

Patient acceptability, safety and access : A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations [PDF]

, 2018
© 2017 Elsevier B.V. All rights reserved.The selection and design of age-appropriate formulations intended for use in paediatric and geriatric patients are dependent on multiple factors affecting patient acceptability, safety and access.
Ernest, Terry B., Liu, Fang, Ranmal, Sejal R., Walsh, Jennifer   +3 more
core   +2 more sources

Automation potential of a new, rapid, microscopy based method for screening drug-polymer solubility [PDF]

, 2020
For the pharmaceutical industry, the preformulation screening of the compatibility of drug and polymeric excipients can often be time-consuming because of the use of trial-and-error approaches.
Alhijjaj, Muqdad, Belton, Peter, Fabian, Laszlo, Qi, Sheng, Reading, Mike   +4 more
core   +1 more source

The Fate of SWCNTs in Mouse Peritoneal Macrophages: Exocytosis, Biodegradation, and Sustainable Retention

Frontiers in Bioengineering and Biotechnology, 2020
The understanding of toxicological and pharmacological profiles of nanomaterials is an important step for the development and clinical application of nanomedicines.
Ping-Xuan Dong, Ping-Xuan Dong, Xinfeng Song, Xinfeng Song, Jiwei Wu, Jiwei Wu, Shuqin Cui, Shuqin Cui, Guizhi Wang, Lianying Zhang, Hanwen Sun, Hanwen Sun   +11 more
doaj   +1 more source

Influence of Excipients and Pressing Force on the Impurity Content of N-(4-aminobenzoyl)-L-glutamic Acid in Folic Acid Drugs During Storage

Разработка и регистрация лекарственных средств, 2023
Introduction. Excipients, impurities contained in them, and sorbed water are one of the reasons for degradation of the active pharmaceutical substance (API). Excipients effect should be especially evaluated for moisture-sensitive APIs. Folic acid (FA) is
N. A. Obraztsova, A. A. Samsonov, M. A. Kovtunenko, V. N. Shmeleva, N. A. Golubeva   +4 more
doaj   +1 more source