Results 31 to 40 of about 76,164 (271)

Stability of Extemporaneously Prepared Rufinamide Oral Suspensions [PDF]

, 2010
Background: Rufinamide is an oral antiepileptic drug indicated for adjunctive therapy in treating generalized seizures associated with Lennox-Gastaut syndrome. Currently, rufinanide is available as 200-mg and 400-mg tablets. A liquid dosage form does not
Best, Robert, Hutchinson, David, Liou, Yayin, Zhao, Fang   +3 more
core   +2 more sources

Different Effects of Strong-Bonded Water with Different Degrees of Substitution of Sodium Sulfobutylether-β-cyclodextrin on Encapsulation

Pharmaceutics
The encapsulation of sodium sulfobutylether-β-cyclodextrin (SBE-β-CD) is influenced not only by the degree of substitution (DS) but also by the presence of strong-bonded water (SBW).
Xiaofeng Wang, Jiaqi Huang, Dengchen Yang, Ting Huang, Yang Yang, Jiasheng Tu, Jian Zou, Huimin Sun, Xia Zhao, Rui Yang   +9 more
doaj   +1 more source

C35 - Formulation et fabrication des suppositoires antipaludiques d’Artémisia annua d’Ouest Cameroun en utilisant le beurre de karité comme excipient

Journal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
Introduction : Le but de la présente étude est de formuler et fabriquer des suppositoires antipaludiques à base des matières premières locales (poudre de feuilles et de tiges de Artemisia annua comme principe actif et beurre de karité amélioré utilisé ...
Lionel Tematio Nague, Emmanuel Mpondo Mpondo, Emmanuel Nnanga Nga, J. S. N. Foumane Maniepi, V. Soppo Lobe, J. A. Metogo Ntsama, A. Minyem , F.C. Mbenga Mekoulou, F. Ngolsou, J. Nko’o, P. Obono, M. Nyangono Ndongo, J. Ze Minkande   +12 more
doaj   +1 more source

(Benzo[h]quinoline-κ²C,N)-[2,2′-bis(diphenylphosphino)-1,1′-binaphthalene-κ²P,P′]-platinum(II) Hexafluorophosphate

Molbank
A cyclometalated platinum(II) complex [Pt(bzq)(BINAP)]PF6 bearing a 2,2′-bis(diphenylphosphino)-1,1′-binaphthalene (BINAP) auxiliary ligand and a cyclometalated benzo[h]quinoline (bzq) ligand have been prepared.
Haoni Wang, Meiting Zhang, Jianwei Wu, Junqi Zhang, Xianglong Meng, Yuliang Yang   +5 more
doaj   +1 more source

Stability of extemporaneously prepared ophthalmic solutions for mydriasis [PDF]

, 2018
Purpose Results of an evaluation of the physical and chemical stability of extemporaneously prepared adult and pediatric ophthalmic solutions containing combinations of phenylephrine, tropicamide, and cyclopentolate are reported.
Camp, Nicole A., Gilbert, Justine M., Hughes, Susan E., Nadra, Jennifer T., Zhao, Fang   +4 more
core   +2 more sources

Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles [PDF]

, 2012
The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels.
Mucalo, Michael R., Rathbone, Michael J.
core   +1 more source

The use of high performance anion exchange chromatography for the detection of counterfeit pharmaceutical products using the excipient content as a marker [PDF]

, 2015
The aim of the investigation described here was to examine the differences between genuine and counterfeit pharmaceutical products through the development of an analytical method capable of rigorously identifying the sugar-based excipients.
Beasley, Emma, Coleman, Tyler, Suman, Mandeesh   +2 more
core   +2 more sources

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Synthesis and crystal structure of ethyl (2S,4aS,6aS,6bR,8aR,12aS,12bR,14bR,E)-10-(((3,4-dichlorobenzyl)oxy)imino)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylate

Zeitschrift für Kristallographie - New Crystal Structures
C39H53Cl2NO4, monoclinic, P21 (no. 4), a = 7.55730(10) Å, b = 11.0989(2) Å, c = 20.9222(3) Å, β = 91.426(1)°, V = 1754.36(5) Å3, Z = 2, Rgt(F) = 0.0360, wRref(F2) = 0.1028, T = 169.98(10) K.
Dong Zhang-Chao, Shen Hui, Mu Ze-Bo, Xu Kai-Hua   +3 more
doaj   +1 more source

European Paediatric Formulation Initiative (EuPFI)-Formulating Ideas for Better Medicines for Children. [PDF]

, 2017
© American Association of Pharmaceutical Scientists 2016, published by Springer US, available online at doi: https://doi.org/10.1208/s12249-016-0584-1The European Paediatric Formulation Initiative (EuPFI), founded in 2007, aims to promote and facilitate ...
C Tuleu, Catherine Tuleu, F Liu, F Liu, Fang Liu, H Batchelor, H Batchelor, H Wachtel, Hannah Batchelor, HK Batchelor, J Walsh, J Walsh, J Walsh, J Walsh, J Walsh, Jenny Walsh, M Pein, Roy Turner, S Salunke, S Salunke, S Salunke, S Salunke, S Salunke, S Salunke, Smita Salunke, T Nunn, T Sam, TB Ernest, Tzuchi Rob Ju   +28 more
core   +4 more sources