Results 61 to 70 of about 46,206 (287)

Development of the composition of the tablets "Cardiosten" using the method of mathematical planning of the experiment

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The aim of the work is devoted to the substantiation of the choice of excipients while the development of Cardiosten tablets with a dry extract from a mixture of medicinal plant materials of cardiological action, taking into account the application of ...
O. S. Kukhtenko, Ye. V. Hladukh
doaj   +1 more source

Understanding the implications of pharmaceutical excipients and additives in the treatment of diabetic foot ulcers [PDF]

, 2016
A diabetic foot ulcer (DFU) is a consequence of Diabetes Mellitus (DM) and involves complex pathological processes. Among diabetic patients DFU is a major cause of deaths resulting from the amputation of the lower limbs. Various treatment strategies have
Gowthamarajan Kuppusamy, Veera Venkata Satyanarayana Reddy Karri, Shashank Mulukutla, Sumeet Sood, Rajkumar Malayandi   +4 more
core  

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Karakterisasi Agar dari Hasil Produksi Petani Kabupaten Brebes sebagai Eksipien Mukoadesif dalam Sediaan Farmasi

Journal of Tropical Pharmacy and Chemistry, 2016
Agar is widely used as a tablet binder, gel base, cream base, and the others in the manufacture of pharmaceutical dosage forms. Mucoadhesive drug delivery is expected to prolong the contact time of the drug in the mucus so that the maximum effect of the
Dhadhang Wahyu Kurniawan, Arif Budianto, Khilman Husna Pratama   +2 more
doaj   +1 more source

Pharmaco-technological researches for development of tablets composition with amlodipin and enalapril

Фармацевтичний журнал, 2020
Ukraine has one of the highest mortality rates from cardiovascular diseases in Europe, accounting for 772.1 cases among men and 440.9 among women per 100 000 population.
N. S. Behei, O. V. Tryhubchak
doaj   +1 more source

Excipients used in lyophilization of small molecules [PDF]

This review deals with the excipients used in various lyophilized formulations of small molecules. The role of excipients such as bulking agents, buffering agents, tonicity modifiers, antimicrobial agents, surfactants and co-solvents has been discussed ...
Arvind Kumar Bansal, Ankit Baheti, Lokesh Kumar   +2 more
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Uncharacterized and uncharacterizable attributes of macromolecular excipients [PDF]

, 2010
Macromolecular excipients are unique in that each (macro)molecule or polymer chain can chemically differ significantly from another. However, these differences may not be detected across different lots or different samples because the analytical methods ...
Apte, Shireesh, Shireesh Apte
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Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Methods of Thermal Analysis as Fast and Reliable Tools for Identification and Quantification of Active Ingredients in Commercially Available Drug Products

Pharmaceutics
Background/Objectives: Drug products on the pharmaceutical market must meet a number of requirements that guarantee their quality, safety, and efficacy.
Marek Wesolowski
doaj   +1 more source

An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations

Pharmaceutics, 2018
Protein-based therapeutics are considered to be one of the most important classes of pharmaceuticals on the market. The growing need to prolong stability of high protein concentrations in liquid form has proven to be challenging.
Akash Pandya, Mark J. Howard, Mire Zloh, Paul A. Dalby   +3 more
doaj   +1 more source