Results 151 to 160 of about 151,712 (215)

A massively parallel CRISPR-based screening platform for modifiers of neuronal depolarization. [PDF]

open access: yesNat Commun
Boggess SC   +14 more
europepmc   +1 more source

Deletion of the calcium-binding protein S100β alters axon initial segment development in the visual cortex. [PDF]

open access: yesFront Cell Neurosci
Inglebert Y   +4 more
europepmc   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

open access: yesAngewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann   +10 more
wiley   +1 more source

Heterogeneous Recruitment Curve Responses to Anodal Transcranial Direct Current Stimulation in Children With Unilateral Spastic Cerebral Palsy. [PDF]

open access: yesNeurorehabil Neural Repair
Metelski N   +5 more
europepmc   +1 more source

Comparative analysis of cytoarchitectonic and neurochemical aspects of the globus pallidus in the rock cavy (Kerodon rupestris) and the common marmoset (Callithrix jacchus)

open access: yesThe Anatomical Record, EarlyView.
Abstract The globus pallidus (GP), a subcortical structure within the basal ganglia, plays a crucial role in modulating cortico‐subcortical circuits related to motor control and associative/limbic functions. However, the cytoarchitectonic and neurochemical organization of this structure remains poorly characterized in naturally existing wild‐type ...
Lavínnya Yáskara de Aquino Matoso   +10 more
wiley   +1 more source

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