Results 91 to 100 of about 1,712,147 (281)

Exciting experiences make neurons less excitable

open access: yeseLife, 2017
Neurons in the brain of a female mouse that respond to the scent of a given male become suppressed after mating.
Prakruti Nanda   +2 more
openaire   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Highly indistinguishable single photons from incoherently and coherently excited GaAs quantum dots

open access: yes, 2019
Semiconductor quantum dots are converging towards the demanding requirements of photonic quantum technologies. Among different systems, quantum dots with dimensions exceeding the free-exciton Bohr radius are appealing because of their high oscillator ...
da Silva, Saimon F. Covre   +8 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A laser excitation scheme for $^{229\text{m}}$Th

open access: yes, 2017
Direct laser excitation of the lowest known nuclear excited state in $^{229}$Th has been a longstanding objective. It is generally assumed that reaching this goal would require a considerably reduced uncertainty of the isomer's excitation energy compared
Kazakov, Georgy   +6 more
core   +2 more sources

Formation of a combined electron-hole emission state in the LiRbSO4 – Eu phosphor

open access: yesҚарағанды университетінің хабаршысы. Физика сериясы
In the irradiated phosphor 4 LiRbSO Eu , the mechanisms of formation of the induced or combined electron-emitting state at 3.1-2.94 eV were studied using optical and thermal activation spectroscopy methods.
Т.Н. Нурахметов   +9 more
doaj   +1 more source

Cell-Type Specificity of Callosally Evoked Excitation and Feedforward Inhibition in the Prefrontal Cortex

open access: yesCell Reports, 2018
Excitation and inhibition are highly specific in the cortex, with distinct synaptic connections made onto subtypes of projection neurons. The functional consequences of this selective connectivity depend on both synaptic strength and the intrinsic ...
Paul G. Anastasiades   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dephasing of quantum dot exciton polaritons in electrically tunable nanocavities

open access: yes, 2009
We experimentally and theoretically investigate dephasing of zero dimensional microcavity polaritons in electrically tunable single dot photonic crystal nanocavities.
A. Laucht   +7 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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