Results 71 to 80 of about 795,847 (338)
Biosensors, 2019 In previous studies, we encountered substantial problems using the CFP_YFP Förster resonance energy transfer (FRET) pair to analyze protein proximity in the endoplasmic reticulum of live cells.
Kira Erismann-Ebner +2 more
doaj +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
On interplay between excitability and geometry [PDF]
arXiv, 2019 A commonly accepted feature of an excitable medium is that a local excitation leads to a propagation of circular or spiral excitation wave-fronts. This is indeed the case in fully excitable medium. However, with a decrease of an excitability localised wave-fragments emerge and propagate ballistically.
arxiv
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Frontiers in Computational Neuroscience, 2012 Neurons often receive massive concurrent bombardment of synaptic inhibition and excitation during functional network activity. This increases membrane conductance and causes fluctuations in membrane potential (Vm) and spike timing.
Jens eKolind +2 more
doaj +1 more source
Cells, 2020 A decrease in synaptic plasticity and/or a change in excitation/inhibition balance have been suggested as mechanisms underlying major depression disorder.
Ipsit Srivastava +4 more
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Collective excitations in Quantum Dot [PDF]
, 1999 We investigate different types of collective excitations in a quantum dot containing finite number of electrons at zero magnetic field. To estimate the excitation energies analytically we follow the energy weighted sum-rule approach. We consider the most general multipole excitation with angular momentum l, and the breathing mode excitation (monopole ...
arxiv +1 more source
Delay-Induced Excitability [PDF]
Physical Review Letters, 2005 We analyse the stochastic dynamics of a bistable system under the influence of time-delayed feedback. Assuming an asymmetric potential, we show the existence of a regime in which the systems dynamic displays excitability by calculating the relevant residence time distributions and correlation times.
Piwonski, Tomasz +3 more
openaire +5 more sources
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source