Results 81 to 90 of about 795,847 (338)

Cell-Type Specificity of Callosally Evoked Excitation and Feedforward Inhibition in the Prefrontal Cortex

Cell Reports, 2018
Excitation and inhibition are highly specific in the cortex, with distinct synaptic connections made onto subtypes of projection neurons. The functional consequences of this selective connectivity depend on both synaptic strength and the intrinsic ...
Paul G. Anastasiades, Joseph J. Marlin, Adam G. Carter   +2 more
doaj   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Axon morphology and intrinsic cellular properties determine repetitive transcranial magnetic stimulation threshold for plasticity

Frontiers in Cellular Neuroscience
IntroductionRepetitive transcranial magnetic stimulation (rTMS) is a widely used therapeutic tool in neurology and psychiatry, but its cellular and molecular mechanisms are not fully understood.
Christos Galanis, Lena Neuhaus, Nicholas Hananeia, Zsolt Turi, Peter Jedlicka, Andreas Vlachos, Andreas Vlachos, Andreas Vlachos   +7 more
doaj   +1 more source

Spin vs charge excitations in heavy-fermion compounds* [PDF]

Acta Physica 1 (2006) 20, 2003
It is pointed out that the answer on the question about the role played by spin and charge excitations will help to solve the physical origin of the heavy- fermion phenomena. Our answer is that neutral spin-like excitations are responsible for the heavy-fermion phenomena whereas the role of the charge excitations is negligible.
arxiv  

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

FEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon, Juho Choi, Youngin Roh, Eunbin Lee, Luigie Villamante, Myung‐Hee Kwon   +5 more
wiley   +1 more source

Dynamical Manipulation of Surface Plasmon Polaritons

Applied Sciences, 2019
As the fundamental and promising branch of nanophotonics, surface plasmon polaritons (SPP) with the ability of manipulating the electromagnetic field on the subwavelength scale are of interest to a wide spectrum of scientists.
Sen Wang, Chunying Zhao, Xing Li
doaj   +1 more source

Excitable Behaviors

, 2018
This chapter revisits the concept of excitability, a basic system property of neurons. The focus is on excitable systems regarded as behaviors rather than dynamical systems. By this we mean open systems modulated by specific interconnection properties rather than closed systems classified by their parameter ranges.
Sepulchre, Rodolphe, Drion, Guillaume, Franci, Alessio   +2 more
openaire   +2 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Corrigendum: Dissipative Magnetic Soliton in a Spinor Polariton Bose–Einstein Condensate

Frontiers in Physics, 2022
Chunyu Jia, Rukuan Wu, Ying Hu, Ying Hu, Wu-Ming Liu, Wu-Ming Liu, Wu-Ming Liu, Zhaoxin Liang   +7 more
doaj   +1 more source

Complex Dynamics of Propagating Waves in a Two-Dimensional Neural Field

Frontiers in Computational Neuroscience, 2019
Propagating waves with complex dynamics have been widely observed in neural population activity. To understand their formation mechanisms, we investigate a type of two-dimensional neural field model by systematically varying its recurrent excitatory and ...
Daniel Naoumenko, Pulin Gong, Pulin Gong
doaj   +1 more source