Results 101 to 110 of about 568,915 (313)

ENERGY TRANSFER IN TRIMERIC C-PHYCOCYANIN STUDIED BY PICOSECOND FLUORESCENCE KINETICS [PDF]

, 1986
The excited state kinetics of trimeric C-phycocyanin from Mastigocladus laminosus has been measured as a function of the emission and excitation wavelength by the single-photon timing technique with picosecond resolution and simultaneous data analysis. A
John, Wolfhart, Scheer, Hugo, Wendler, J., Holzwarth, A. R.   +3 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Detection of composite damage by IR NDT using ultrasonic and optic excitation

MATEC Web of Conferences, 2019
The submitted paper presents experience with detection of damaged composites by means of an ultrasonic excitation system in comparison with an optic system of excitation. In case of the ultrasonic excitation system is a high-frequency signal modulated by
Dekýš Vladimír, Štalmach Ondrej, Soukup Josef, Sapietová Alžbeta, Rychlíková Lenka   +4 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Excitation System Output Quantities-Based Loss of Excitation Detection in Synchronous Generators

IEEE Open Access Journal of Power and Energy
In the earliest generation of loss of excitation (LOE) protection relays, the exciter’s output voltage ( $V_{e}$ ) or output current ( $I_{e}$ ) were employed for the LOE protection of synchronous generators (SGs) by employing under-voltage or ...
Abbas Hasani, Xiaodong Liang, Majid Sanaye-Pasand, Moein Abedini   +3 more
doaj   +1 more source

Linear Active Disturbance Rejection Control for Flexible Excitation System of Pumped Storage Units

The role of pumped storage in global energy structure transformation is becoming increasingly prominent. This article introduces a flexible excitation system based on fully controlled device converters into pumped storage units (PSUs). It can address the
Xinyu Cheng, Sisi Jia, Jun Qin, Jiayao Li, Bo Zhao, Jiandong Zheng, Dan Wang   +6 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cardiorespiratory system as system with limited excitation

, 2019
A new modified cardiorespiratory model based on the famous DeBoer beat-to-beat model and Zaslavsky map (which describes dynamics of the respiratory system as a generator of central type) was studied in details.
Krasnopolskaya, T. S., Rudnytska, M. O., Pechuk, E. D.   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source