Results 91 to 100 of about 45,262,696 (341)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Mathematical model of mini-CHP based on salient-pole synchronous generator

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов, 2019
Many factors affect transients in electrical systems with mini-CHP. Development of a reciprocating gas engine mathematical model based on a salient-pole synchronous generator will improve the calculations accuracy of transient and system stability.
Gennadiy Vagin   +3 more
doaj   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Novel Flexible Excitation System Based on MultilevelTopology Technology

open access: yesZhongguo dianli, 2019
Based on the development trend of the next generation power system, a novel flexible excitation system is designed based on three-level voltage source converter, and a matching five-level DC chopping circuit is proposed.
Kuayu WU   +6 more
doaj   +1 more source

Bio-impedance Excitation System: A Comparison of Voltage Source and Current Source Designs

open access: yes, 2013
The key component in any bio-impedance measurement system is the excitation subsystem. Bio-impedance measurement can be performed by applying either current or voltage through the electrodes and then by measuring the resulting voltages or current ...
T. Qureshi, C. Chatwin, Wei Wang
semanticscholar   +1 more source

Internal resonance between in-plane and out-of-plane modes of vibration of inclined cables subjected to vertical support excitation [PDF]

open access: yes, 2011
Inclined cables are important structural elements of cable-stayed bridges. When the bridge deck oscillates, large amplitude cable vibrations can arise in various modes as a result of the low cable damping, parametric excitation or non-linear modal ...
Wagg, DJ   +7 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A SYSTEMATIC REVIEW ON IDENTIFICATION OF EXCITATION SYSTEMS FOR SYNCHRONOUS GENERATORS REVISIÓN SISTEMÁTICA EN IDENTIFICACIÓN DE SISTEMAS DE EXCITACIÓN PARA GENERADORES SINCRÓNICOS REVISÃO SISTEMÁTICA EM IDENTIFICAÇÃO DE SISTEMAS DE EXCITAÇÃO PARA GERADORES SINCRÓNICOS

open access: yesRevista EIA, 2012
This paper presents the state of the art on system identification applied to excitation systems. First, general overviews about system identification and excitation systems for synchronous generators are presented, highlighting the unique characteristics
Andrés Julián Saavedra-Montes   +2 more
doaj  

Segmented excitation for electrical capacitance tomography [PDF]

open access: yes, 2014
Electrical Capacitance Tomography (ECT) system offers a non-invasive measurement for flow properties within pipelines. The resolution of the images can be improved by utilizing more electrodes within the sensing area which causes reduction in size, but ...
Mohammad Din, Shahrulnizahani
core  

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