Results 71 to 80 of about 568,915 (313)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Multiple excitations in photosynthetic systems

open access: yesBiophysical Journal, 1976
The yield of fluorescence in Chlorella from a 7 ns pulse of light is found to decrease gradually as a function of the number of hits in the photosynthetic units. The fivefold decrease in yield is spread over some three orders of magnitude of pulse energy and strongly suggests another random process in addition to that of photon absorption.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Design, Modeling and Experimental Validation of a Variable Resonant Electro-Hydraulic Fatigue Testing System

open access: yesIEEE Access, 2019
High frequency excitation in the electro-hydraulic mode, especially kilohertz regime, has already been realized owing to the merits of specially designed two-dimensional rotary valve (2D rotary valve).
Yan Ren, Jiping Bai, Jian Ruan
doaj   +1 more source

Low Excitation Corrections to the Density Of States [PDF]

open access: yes, 2007
We study a many particle system contained within a harmonic oscillator potential, with the single particle spacings equispaced and nondegenerate. We consider either fermions or bosons within this harmonic oscillator potential and derive the density of ...
Jelovic, Andrijan
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Cascaded Voltage-Control Method for a Diode-Front-End-Based Variable-Speed Synchronous Generator in a DC Power System

open access: yesIEEE Access
This paper proposes a novel cascade voltage-control method for DC variable-speed synchronous generators with a diode rectifier. In order to emphasize the necessity of the proposed method, the light-load voltage fluctuation problem that affects the ...
Sung-Soo Min, Kyoung-Min Choo
doaj   +1 more source

Development of transverse excitation MFL inline detector

open access: yesYou-qi chuyun, 2020
A transverse excitation magnetic flux leakage (MFL) inline detector, with a diameter of 711 mm, was developed in response to the difficulty in detecting axial metal loss defects of long-distance oil and gas pipelines.
Chao YU   +6 more
doaj   +1 more source

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