Results 81 to 90 of about 1,254,288 (295)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Definition of a linear equivalent model for a non-linear system with impacts [PDF]

open access: yes, 2012
Modal characteristics of non-linear system are typically studied through response to harmonic excitation and using various definitions of non-linear modes. However, few results are available for systems under broadband excitation.
BALMES, Etienne   +2 more
core   +3 more sources

The generalized Kadanoff-Baym ansatz. Computing nonlinear response properties of finite systems

open access: yes, 2012
For a minimal Hubbard-type system at different interaction strengths U, we investigate the density-response for an excitation beyond the linear regime using the generalized Kadanoff-Baym ansatz (GKBA) and the second Born (2B) approximation.
Balzer, K., Bonitz, M., Hermanns, S.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Excitation spectrum and instability of a two-species Bose-Einstein condensate

open access: yes, 1998
We numerically calculate the density profile and excitation spectrum of a two-species Bose-Einstein condensate for the parameters of recent experiments.
B. D. Esry   +12 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A SYSTEMATIC REVIEW ON IDENTIFICATION OF EXCITATION SYSTEMS FOR SYNCHRONOUS GENERATORS REVISIÓN SISTEMÁTICA EN IDENTIFICACIÓN DE SISTEMAS DE EXCITACIÓN PARA GENERADORES SINCRÓNICOS REVISÃO SISTEMÁTICA EM IDENTIFICAÇÃO DE SISTEMAS DE EXCITAÇÃO PARA GERADORES SINCRÓNICOS

open access: yesRevista EIA, 2012
This paper presents the state of the art on system identification applied to excitation systems. First, general overviews about system identification and excitation systems for synchronous generators are presented, highlighting the unique characteristics
Andrés Julián Saavedra-Montes   +2 more
doaj  

Interband heating processes in a periodically driven optical lattice

open access: yes, 2016
We investigate multi-"photon" interband excitation processes in an optical lattice that is driven periodically in time by a modulation of the lattice depth.
Eckardt, André, Sträter, Christoph
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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