Results 111 to 120 of about 568,915 (313)

Higher Order Parametric Excitation Modes for Spaceborne Quadrupole Mass Spectrometers [PDF]

open access: yes, 2011
This paper describes a technique to significantly improve upon the mass peak shape and mass resolution of spaceborne quadrupole mass spectrometers (QMSs) through higher order auxiliary excitation of the quadrupole field.
Block, B. P.   +12 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Evaluasi Pola Tingkah Laku Tegangan Sistem Eksitasi Generator Dengan Metoda Penempatan Kutub Menggunakan Algoritma Bass–Gura

open access: yesJurnal Nasional Teknik Elektro, 2012
In power systems, the behavior patterns of excitation system voltage is very important to note because it can affect the voltage stability of the power system.
Heru Dibyo Laksono, Noris Fredi Yulianto
doaj   +1 more source

Excitation function of (p, alpha) nuclear reaction on enriched 67Zn: Possibility of production of 64Cu at low energy cyclotron

open access: yes, 2014
The potential for production of the medically relevant 64Cu has been investigated by proton irradiation of highly enriched 67Zn targets. The excitation function of the 67Zn(p, α)64Cu a nuclear reaction was measured by the stacked-foil technique up to 30 ...
Nagatsu, Kotaro   +2 more
core  

Energy harvesting from vibrations with a nonlinear oscillator

open access: yes, 2009
In this paper we present a nonlinear electromagnetic energy harvesting device that has a broadly resonant response. The nonlinearity is generated by a particular arrangement of magnets in conjunction with an iron-cored stator.
Clare, Lindsay R.   +11 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

HMM-based Speech Synthesis with an Acoustic Glottal Source Model [PDF]

open access: yes, 2009
A major cause of degradation of speech quality in HMM-based speech synthesis is the use of a simple delta pulse signal to generate the excitation of voiced speech. This paper describes a new approach to using an acoustic glottal source model in HMM-based
Renals, Steve   +4 more
core  

Power system stabilizer with the IEEE type-ST1 excitation system.

open access: yes, 2016
Power system stabilizer with the IEEE type-ST1 excitation system.
Azah Mohamed (844453)   +3 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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