The Role of Calcium-Permeable Kainate and AMPA Receptors in the Leading Reaction of GABAergic Neurons to Excitation. [PDF]
Zinchenko VP +8 more
europepmc +1 more source
4-Aminopyridine reveals presynaptic GABA actions in rat sympathetic ganglia [PDF]
Galvan, Martin +2 more
core
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Crosstalk Between Glycinergic and N-Methyl-D-Aspartate Receptor-Mediated Glutamatergic Transmission in Behaviours Associated with Opioid Use Disorder. [PDF]
Essmat N +13 more
europepmc +1 more source
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic +2 more
wiley +1 more source
Cardiac endogenous transmitter system: molecular features, functions, and clinical implications. [PDF]
Xie D, Liang D, Zhou L, Liu Y, Chen YH.
europepmc +1 more source
Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller +5 more
wiley +1 more source
EAR-20 peptide, a novel NMDA receptor positive allosteric modulator. [PDF]
García-Díaz R +11 more
europepmc +1 more source
An acid‐responsive polymeric micelle system based of aliphatic poly(carbonate)s with benzyl ketal side chains is designed for targeted immunodrug delivery. It can disassemble in endosomal environments, enabling site‐specific immunoactivation and enhanced biodegradability.
Adrian V. Hauck +16 more
wiley +1 more source
Cancer Neuroscience: Linking Neuronal Plasticity with Brain Tumor Growth and Resistance. [PDF]
Khafaga DSR +7 more
europepmc +1 more source

