Results 91 to 100 of about 44,335 (335)

TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia

Neurobiology of Disease
Excitotoxicity arises from unusually excessive activation of excitatory amino acid receptors such as glutamate receptors. Following an energy crisis, excitotoxicity is a major cause for neuronal death in neurological disorders. Many glutamate antagonists
Charlene P. Poore, Nurul A.M.N. Hazalin, Shunhui Wei, See Wee Low, Bo Chen, Bernd Nilius, Zurina Hassan, Ping Liao   +7 more
doaj   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

The neurochemical basis of photic entrainment of the circadian pacemaker [PDF]

Circadian rhythmicity in mammals is controlled by the action of a light-entrainable hypothalamus, in association with two cell clusters known as the supra chiasmatic nuclei (SCN).
Buckley, Becky, Lutton, Lewis M., Rea, Michael A.   +2 more
core   +1 more source

The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia [PDF]

, 2019
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
A.M. Lavoie, AR Woodruff, C Börgers, C-G Hahn, CA Brenner, Chi-Ming A. Chen, CL Beasley, D Vierling-Claassen, D Vierling-Claassen, David A. Lewis, David W. Volk, E Salinas, G Gonzalez-Burgos, GA Light, GP Krishnan, Hanna Thuné, Henry Markram, I Wonodi, J. Szabadics, Joshua T. Kantrowitz, JS Kwon, KM Spencer, KM Spencer, KM Spencer, L KRISTIANSEN, LS Overstreet, M Bartos, M Carlén, Monica Beneyto, Monika P. Jadi, MW Howard, N Hajos, Nadezhda V. Povysheva, P Fries, P Steullet, P Teale, Pascal Fries, R Tsuchimoto, Robin Tremblay, RY Cho, S Keros, T Hashimoto, T Mäki-Marttunen, T-U Woo, Tuomo Mäki-Marttunen, Y Kawaguchi   +45 more
core   +2 more sources

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Multifunctional Microstructured Surfaces by Microcontact Printing of Reactive Microgels

Advanced Functional Materials, EarlyView.
Reactive poly(N‐vinylcaprolactam‐co‐glycidyl methacrylate) microgels are used as functional inks to create surface‐grafted arrays on glass via microcontact printing. The patterns (10–50 µm widths and spacings) enable stable binding and post‐functionalization with dyes and peptides.
Inga Litzen, Alexander Töpel, Martin Zenke, Antonio Sechi, Andrij Pich   +4 more
wiley   +1 more source

Bol i ekscitatorne aminokiseline [PDF]

Vojnosanitetski Pregled, 2002
Jelenković Ankica V., Veskov Rosica, Jovanović Marina D., Raičević Ranko, Bokonjić Dubravko, Vasilev-Pešić Vesna, Bošković Bogdan   +6 more
doaj   +1 more source

Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat [PDF]

, 2007
The administration of noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine and ketamine has been shown to increase the extracellular concentration of glutamate and serotonin (5-HT) in the medial prefrontal cortex (mPFC ...
López-Gil, Xavier, Babot, Zoila, Amargós-Bosch, Mercè, Suñol, Cristina, Artigas, Francesc, Adell, Albert   +5 more
core   +1 more source

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

Neuroprotective Effect of Excitatory Amino Acid Receptor Antagonist on Retina of Rat

, 2021
Chuanfeng Fan, Wenguo Feng, Jingchang Yang, Qingchao Chen, Yu Tian Wang   +4 more
openalex   +1 more source