Advanced Science, EarlyView.Graphic illustration showing the strategic approaches based on the currently investigated evidence of psychedelics that suggests the challenges and how to address the prescription of mental disorders. These applicable avenues may provide substantial insight into distinguishing between brain networks and psychedelics.
Sung‐Hyun Kim +5 more
wiley +1 more source
Neonatal Nonketotic Hyperglycinemia: A Severe Case With Prenatal Indicators and Comprehensive Review of Recognition and Management. [PDF]
Clin Case RepParviz S, Hooshyar D.
europepmc +1 more source
Advanced Science, EarlyView.The target of rapamycin (TOR) complex is a central plant growth regulator. Here, the protein–protein interactions underlying its various functions are mapped by pupylation‐based proximity‐labeling in Arabidopsis, using TOR complex subunits LST8‐1 and RAPTOR1, alongside TOR inhibitor FK506‐binding protein, as baits.
Shuai Zheng +9 more
wiley +1 more source
Pathophysiology and Management Strategies for Post-Stroke Spasticity: An Update Review. [PDF]
Int J Mol SciChen B +5 more
europepmc +1 more source
Direct Quantification of Protein–Protein Interactions in Living Bacterial Cells
Advanced Science, EarlyView.Quantitative measurement of protein–protein interactions in living cells is vital for biotechnology applications. Fluorescence resonance energy transfer (FRET) signals in bacterial cells are often weak, leading to false‐positive. Quantitative FRET measurements are implemented to overcome the weak FRET signal.
Soojung Yi +12 more
wiley +1 more source
Deciphering the Functions of Raphe-Hippocampal Serotonergic and Glutamatergic Circuits and Their Deficits in Alzheimer's Disease. [PDF]
Int J Mol SciYu W, Zhang R, Zhang A, Mei Y.
europepmc +1 more source
Photopatternable PEDOT:PSS Hydrogels for High‐Resolution Photolithography
Advanced Science, EarlyView.A photosensitive biphasic conducting polymer hydrogel (PB‐CH) is rationally designed with PEDOT:PSS as the conductive phase and a light‐sensitive matrix as the mechanical phase. Such a PB‐CH offers a unique combination of excellent conductivity (≈30 S cm⁻¹), robust mechanical performance (with stretchability up to 50%), and high photopatternability ...
Wen Wang +7 more
wiley +1 more source
Control of Synaptotagmin-1 Trafficking by SV2A-Mechanism and Consequences for Presynaptic Function and Dysfunction. [PDF]
J NeurochemHogg JA, Cousin MA.
europepmc +1 more source
Advanced Science, EarlyView.This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang +9 more
wiley +1 more source
Molecular Anatomy of Synaptic and Extrasynaptic Neurotransmission Between Nociceptive Primary Afferents and Spinal Dorsal Horn Neurons. [PDF]
Int J Mol SciAntal M.
europepmc +1 more source