Results 301 to 310 of about 70,307 (362)

The isomers of 2-amino-5-phosphonovalerate as excitatory amino acid antagonists—A reappraisal

European Journal of Pharmacology, 1982
Abstract The previously reported qualitative similarity of action of the optical isomers of 2-amino-phosphonovalerate (AVP) as antagonists of certain excitatory amino acid actions is incorrect. Optically pure L(+)-APV is devoid of such effect; its only action upon neurones may be a very slight excitatory one.
openaire   +2 more sources

Excitatory amino acid antagonists and epilepsy

Biochemical Society Transactions, 1993
A G, Chapman, B S, Meldrum
openaire   +2 more sources

Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists

Pain, 1989
T. Yaksh
semanticscholar   +1 more source

Quinoxalinediones as Excitatory Amino Acid Antagonists in The Vertebrate Central Nervous System

1990
Publisher Summary Excitatory amino-acid receptors (EAARs) are the prime mediators of fast excitatory synaptic transmission in the vertebrate central nervous system (CNS). These receptors are currently classified into five subtypes: N -methyl- d -aspartate (NMDA), α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA), kainate, L -2-amino-4 ...
S N, Davies, G L, Collingridge
openaire   +2 more sources

Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity

The Journal of comparative neurology, 1994
J. Puel, J. Puel, R. Pujol, F. Tribillac, S. Ladrech, M. Eybalin   +5 more
semanticscholar   +1 more source

Spinal pharmacology of thermal hyperesthesia induced by constriction injury of sciatic nerve. Excitatory amino acid antagonists

Pain, 1992
Tatsuo Yamamoto, T. Yaksh
semanticscholar   +1 more source

Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines.

TIPS - Trends in Pharmacological Sciences, 1993
M. Rogawski
semanticscholar   +1 more source

Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat

Brain Research, 1990
A. Dickenson, A. F. Sullivan
semanticscholar   +1 more source

Novel class of amino acid antagonists at non-N-methyl-D-aspartic acid excitatory amino acid receptors. Synthesis, in vitro and in vivo pharmacology, and neuroprotection.

Journal of Medicinal Chemistry, 1991
P. Krogsgaard‐Larsen, J. Ferkany, E. Nielsen, U. Madsen, B. Ebert, J. S. Johansen, N. Diemer, T. Bruhn, D. Beattie, D. R. Curtis   +9 more
semanticscholar   +1 more source

Effects of excitatory amino acid antagonists on synaptic responses of supraoptic neurons in slices of rat hypothalamus.

Journal of Neurophysiology, 1990
V. Gribkoff, F. Dudek
semanticscholar   +1 more source