Results 221 to 230 of about 408,389 (348)

Advances in blood‐based phosphorylated tau protein biomarkers and their detection technology for Alzheimer's disease

open access: yesVIEW, EarlyView.
Abstract Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized primarily by memory loss and impaired cognitive function. With the aging world population, the incidence of AD is rising, imposing substantial medical and economic burdens on society.
Shiyuan Fu   +3 more
wiley   +1 more source

Chinese Clinical Practice Guidelines for Auditory Neuropathy (gCAN)

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Auditory neuropathy (AN) is an auditory disorder that affects the function of the auditory pathway. An increasing number of AN cases have been identified with the revelation of the underlying mechanisms, the advancements of diagnostic and detecting techniques.
Chinese Multi‐Center Research Collaborative Group on Clinical Diagnosis and Intervention of Auditory Neuropathy; Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Society of Otorhinolaryngology Head and Neck Surgery   +43 more
wiley   +1 more source

Molecular organization of central cholinergic synapses. [PDF]

open access: yesProc Natl Acad Sci U S A
Rosenthal JS   +10 more
europepmc   +1 more source

The Effect of Advancing Age and Intraocular Pressure Injury on Retinal Ganglion Cell Function and Synaptic Connectivity

open access: yesAging Cell, EarlyView.
The effect of advancing age and intraocular pressure injury on retinal ganglion cell function and synaptic connectivity. While young mice modulate their synaptic input to recover retinal ganglion cell function following injury, older mice compensate by altering their action potential threshold and axon initial segment (AIS) length to increase intrinsic
Vicki Chrysostomou   +9 more
wiley   +1 more source

Erratum to: Active decay of composite excitatory postsynaptic potentials in hippocampal slices from young rats

open access: bronze, 2003
Mikhail G. Dozmorov   +6 more
openalex   +1 more source

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age‐Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

open access: yesAging Cell, EarlyView.
Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik   +20 more
wiley   +1 more source

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