NEURD offers automated proofreading and feature extraction for connectomics. [PDF]
Celii B+57 more
europepmc +1 more source
Mechanisms underlying CSD initiation implicated by genetic mouse models of migraine. [PDF]
Pietrobon D, Brennan KC.
europepmc +1 more source
Establishing a Mouse Model of NL3R617W-Associated Autism Spectrum Disorder for a Functional Study. [PDF]
Gao W, Cai Q, Ying X, Zhao B.
europepmc +1 more source
Mdga2 deficiency leads to an aberrant activation of BDNF/TrkB signaling that underlies autism-relevant synaptic and behavioral changes in mice. [PDF]
Zhao D+9 more
europepmc +1 more source
Fetal growth restriction adversely impacts trajectory of hippocampal neurodevelopment and function
Hippocampal neuron dendritogenesis occurs rapidly in late fetal gestation and forms the foundation for connectivity and long term function. Fetal growth restriction caused by placental insufficiency is associated with reduced dendritogenesis in hippocampal neurons, resulting in a significant decrease in the trajectory of neuro‐development.
Ingrid Dudink+15 more
wiley +1 more source
Serotonin regulates in a cell-type specific manner light-evoked response and synaptic activity in mouse retinal ganglion cells. [PDF]
Di Berardino C+3 more
europepmc +1 more source
Dopamine increases protein synthesis in hippocampal neurons enabling dopamine-dependent LTP. [PDF]
Fuchsberger T+5 more
europepmc +1 more source
ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison+15 more
wiley +1 more source
Supraspinal facilitation of painful stimuli by glutamatergic innervation from the retrosplenial to the anterior cingulate cortex. [PDF]
Hao S+12 more
europepmc +1 more source
Progress on the development of Class A GPCR‐biased ligands
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales+20 more
wiley +1 more source