Results 41 to 50 of about 72,565 (297)

Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in C. elegans [PDF]

, 2019
Mutations in pre-synaptic voltage gated calcium channels can lead to familial hemiplegic migraine type 1 (FHM1). While mammalian studies indicate that the migraine brain is hyperexcitable due to enhanced excitation or reduced inhibition, the molecular ...
Alkema, Mark J., Francis, Michael M., Gao, Shangbang, Grant, Jeff, Huang, Yung Chi, Mulcahy, Ben, Pirri, Jennifer K., Rayes, Diego Hernán, Saheki, Yasunori, Zhen, Mei   +9 more
core   +1 more source

Activity-Dependent Increases in Quantal Size at the Drosophila NMJ

Journal of Developmental Biology
We examined whether an increase in synaptic activity resulted in an increase in quantal size at the neuromuscular junction (NMJ) of third-instar Drosophila larvae.
Andrew S. Powers, Petar Gajic, Ethan Rittereiser, Kavindra Dasrat, Gregory A. Lnenicka   +4 more
doaj   +1 more source

Compressed Sensing of Excitatory Postsynaptic Potential Bio-Signals

Computer Science & Information Technology ( CS & IT ), 2016
To reduce the size of the biosignal data is important because a huge amount of data is made by various experiments. In the paper, we efficiently compress the excitatory postsynaptic potentials (EPSPs) which is one of the biosignal types. To the best of authors' knowledge, EPSPs compression has not been studied yet.
Hyejin An, Hyun-Chool Shin
openaire   +1 more source

Accumulation of Dense Core Vesicles in Hippocampal Synapses Following Chronic Inactivity. [PDF]

, 2018
The morphology and function of neuronal synapses are regulated by neural activity, as manifested in activity-dependent synapse maturation and various forms of synaptic plasticity.
Bi, Guo-Qiang, Lau, Pak-Ming, Liu, Yun-Tao, Tao, Chang-Lu, Zhou, Z Hong   +4 more
core   +2 more sources

Brain injury impairs working memory and prefrontal circuit function

Frontiers in Neurology, 2015
More than 2.5 million Americans suffer a traumatic brain injury (TBI) each year. Even mild to moderate traumatic brain injury causes long-lasting neurological effects.
Colin James Smith, Colin James Smith, Guoxiang eXiong, Jaclynn eElkind, Brendan James Putnam, Akiva eCohen   +5 more
doaj   +1 more source

A biophysical observation model for field potentials of networks of leaky integrate-and-fire neurons

, 2012
We present a biophysical approach for the coupling of neural network activity as resulting from proper dipole currents of cortical pyramidal neurons to the electric field in extracellular fluid.
Graben, Peter beim, Rodrigues, Serafim
core   +2 more sources

Calcium channels controlling acetylcholine release from preganglionic nerve terminals in rat autonomic ganglia [PDF]

, 1999
Little is known about the nature of the calcium channels controlling neurotransmitter release from preganglionic parasympathetic nerve fibres. In the present study, the effects of selective calcium channel antagonists and amiloride were investigated on ...
A.B Smith, Boot, Bowersox, Brock, Brock, D.J Adams, De Luca, Dunlap, Gonzalez-Burgos, Hong, Ireland, L Motin, Lavidis, Lin, Lundy, McDonough, Meir, N.A Lavidis, Randall, Randall, Rogers, Seabrook, Smith, Smith, Smith, Smith, Snider, Tabatabai, Tang, Todorovic, Warren, Waterman, Wright, Wu   +33 more
core   +1 more source

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett, Syeda Amrah Hashmi, Amaan Qureshi, Heather Spader, Shayan Moosa, Ifrah Zawar   +5 more
wiley   +1 more source

The effect of heterogeneity on decorrelation mechanisms in spiking neural networks: a neuromorphic-hardware study [PDF]

, 2014
High-level brain function such as memory, classification or reasoning can be realized by means of recurrent networks of simplified model neurons. Analog neuromorphic hardware constitutes a fast and energy efficient substrate for the implementation of ...
Diesmann, Markus, Grübl, Andreas, Jordan, Jakob, Meier, Karlheinz, Pfeil, Thomas, Schemmel, Johannes, Tetzlaff, Tom   +6 more
core   +5 more sources

Intermediate Resistive State in Wafer‐Scale Vertical MoS2 Memristors Through Lateral Silver Filament Growth for Artificial Synapse Applications

Advanced Functional Materials, EarlyView.
In MOCVD MoS2 memristors, a current compliance‐regulated Ag filament mechanism is revealed. The filament ruptures spontaneously during volatile switching, while subsequent growth proceeds vertically through the MoS2 layers and then laterally along the van der Waals gaps during nonvolatile switching.
Yuan Fa, Milan Buttberg, Ke Ran, Rana Walied Ahmad, Dennis Braun, Lukas Völkel, Jimin Lee, Sofía Cruces, Bart Macco, Bárbara Canto, Holger Lerch, Thorsten Wahlbrink, Holger Kalisch, Michael Heuken, Andrei Vescan, Joachim Mayer, Zhenxing Wang, Ilia Valov, Stephan Menzel, Max C. Lemme   +19 more
wiley   +1 more source