Results 131 to 140 of about 4,862,998 (353)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Generation of Triplet Excited States via Photoinduced Electron Transfer in meso-anthra-BODIPY: Fluorogenic Response toward Singlet Oxygen in Solution and in Vitro.

open access: yesJournal of the American Chemical Society, 2017
Heavy atom-free BODIPY-anthracene dyads (BADs) generate locally excited triplet states by way of photoinduced electron transfer (PeT), followed by recombination of the resulting charge-separated states (CSS). Subsequent quenching of the triplet states by
M. Filatov   +10 more
semanticscholar   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Charge transport and excited states in organic semiconductors

open access: yes, 2011
PhDOrganic semiconductors are of increasing technological interest in applications such as light emitting diodes, field effect transistors, and photovoltaic devices In order to reveal the basic principles behind these organic semiconductors, charge ...
Song, Jingyao
core  

Excited state spatial distributions in a cold strontium gas [PDF]

open access: yes, 2012
This thesis describes the development of a new technique for measuring the spatial distribution of Rydberg atoms in a cold strontium gas. Strontium atoms are cooled and trapped in a magneto-optical trap and coherently excited to Rydberg states in a two ...
LOCHEAD, GRAHAM
core  

Molecular excited states through a machine learning lens

open access: yesNature Reviews Chemistry, 2021
Pavlo O. Dral, M. Barbatti
semanticscholar   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Fromage: A Library for the Study of Molecular Crystal Excited States at the Aggregate Scale

open access: yes, 2019
The study of photoexcitations in molecular aggregates faces the twofold problem of the increased computational cost associated with excited states and the complexity of the interactions among the constituent monomers. A mechanistic investigation of these
Warda, Rahim   +4 more
core   +1 more source

Electron–phonon processes of the silicon-vacancy centre in diamond

open access: yesNew Journal of Physics, 2015
We investigate phonon induced electronic dynamics in the ground and excited states of the negatively charged silicon-vacancy ( ${\rm Si}{{{\rm V}}^{-}}$ ) centre in diamond.
Kay D Jahnke   +8 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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