Results 241 to 250 of about 95,867 (358)

Long-Term Cortical Atrophy after Excitotoxic Striatal Lesion: Effects of Intrastriatal Fetal-Striatum Grafts and Implications for Huntington Disease [PDF]

, 2001
Ana Muñoz, Ana López, Héctor J. Caruncho, María J. Guerra, José L. Labandeira‐García   +4 more
openalex   +1 more source

Ferroptosis Contributes to Retinal Ganglion Cell Loss in GLAST Knockout Mouse Model of Normal Tension Glaucoma. [PDF]

Invest Ophthalmol Vis Sci
Ye H, Feng Y, Xiang W, Lin Z, Li Y, Hu W, Liu K, Tao S, Shu Q, Wang J, Xu F, Xu Y, Wei Y, Huang J.   +13 more
europepmc   +1 more source

Molecular Mechanisms, Endurance Athlete, and Synergistic Therapeutic Effects of Marine‐Derived Antioxidant Astaxanthin Supplementation and Exercise in Cancer, Metabolic Diseases, and Healthy Individuals

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
In metabolic disease, astaxanthin reduces lactate and carbohydrate (CHO) oxidation, while increasing fat oxidation, suggesting improved metabolic efficiency. In relation to exercise, astaxanthin enhances mitochondrial protection and biogenesis, boosts capillary blood flow, and improves oxygen delivery, all of which could lead to better endurance and ...
Wenwen Nie, Jianmin Li, Sogand Rajabi
wiley   +1 more source

Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death [PDF]

, 2001
Weihai Ying, Mary B. Sevigny, Yongmei Chen, Raymond A. Swanson   +3 more
openalex   +1 more source

Restoring Homeostasis: Treating Amyotrophic Lateral Sclerosis by Resolving Dynamic Regulatory Instability. [PDF]

Int J Mol Sci
Lee AJB, Bi S, Ridgeway E, Al-Hussaini I, Deshpande S, Krueger A, Khatri A, Tsui D, Deng J, Mitchell CS.   +9 more
europepmc   +1 more source

Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity‐induced axonal degeneration

The FASEB Journal, 2017
P. Vaur, B. Brugg, M. Mericskay, Zhenlin Li, Mark S. Schmidt, D. Vivien, C. Orset, E. Jacotot, C. Brenner, Eric Duplus   +9 more
semanticscholar   +1 more source

Hyperhomocysteinemia‐Driven Ischemic Stroke: Unraveling Molecular Mechanisms and Therapeutic Horizons

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Neurotoxicity of Hcy. (A figure that best represents the scope of the paper.) Homocysteine can reduce the tightness of endothelial cell connections, increase vascular permeability, and damage the blood–brain barrier. Homocysteine activates various glutamate receptors on the surfaces of neurons and glial cells, triggering excitotoxicity, promoting the ...
Bin Li, Yushun Kou, Lingna Zhang, Lin Yi
wiley   +1 more source

Neuroprotection by Δ⁹-Tetrahydrocannabinol, the Main Active Compound in Marijuana, against Ouabain-InducedIn VivoExcitotoxicity [PDF]

, 2001
Mario van der Stelt, Wouter B. Veldhuis, P.R. Bär, Gerrit A. Veldink, Johannes F.G. Vliegenthart, Klaas Nicolay   +5 more
openalex   +1 more source

Dichloromethane Extract from <i>Amburana cearensis</i> (Allemão) A.C. Sm. Seeds and Its Coumarin Reduce ROS Production and Protect PC12 Cells Against Glutamate Excitotoxicity and Oxygen-Glucose Deprivation. [PDF]

Antioxidants (Basel)
Sanches FS, Ramos FDS, Costa CCOS, Nascimento RPD, Souza BSF, Costa MFD, Costa SL, Ribeiro PR, Ferreira RS, Silva VDAD.   +9 more
europepmc   +1 more source

Lanthionine Ketimine Ethyl Ester Induces Proliferation and Maturation and Regulates Calcium Flux in Primary Mouse Oligodendrocyte Progenitor Cells

Journal of Neuroscience Research, Volume 103, Issue 7, July 2025.
LKE increased OPC proliferation and maturation. LKE reduced Ca responses to ATP and glutamate, and increased responses to KCl. Similar effects occurred with a peptide that disrupts Collapsin Response Mediator Protein 2 interactions with NMDARs and VGCCs.
Veronica T. Cheli, Swathi G. Tumuluri, Zachary McDonald, Travis T. Denton, Jeffrey L. Dupree, Pablo M. Paez, Douglas L. Feinstein   +6 more
wiley   +1 more source