Results 251 to 260 of about 95,867 (358)

Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity [PDF]

, 2001
Pat Manzerra, M. Margarita Behrens, Lorella M.T. Canzoniero, Xue Wang, Valérie Heidinger, Tomomi Ichinose, Shan Ping Yu, Dennis W. Choi   +7 more
openalex   +1 more source

NMDA Receptors: Next therapeutic targets for Tinnitus? [PDF]

Biochem Biophys Rep
Che C, Wu Y, Sun S.
europepmc   +1 more source

Current Concepts of Excitotoxicity [PDF]

Journal of Neuropathology and Experimental Neurology, 1996
openaire   +3 more sources

Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases

MedComm, Volume 6, Issue 7, July 2025.
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar, Sana Khurshid Baba, Inamu Rashid Khan, Mohd Shahnawaz Khan, Fohad Mabood Husain, Saheem Ahmad, Mohammad Haris, Mayank Singh, Ammira S. Al‐Shabeeb Akil, Muzafar A. Macha, Ajaz A. Bhat   +10 more
wiley   +1 more source

Effects of Volatile Anesthetics on N -methyl-d-aspartate Excitotoxicity in Primary Rat Neuronal–Glial Cultures [PDF]

, 2001
Masaya Kudo, Mitsuo Aono, Yoonki Lee, Gary W. Massey, Robert D. Pearlstein, David S. Warner   +5 more
openalex   +1 more source

Xenon in ALS Treatment: What Are We Waiting for? [PDF]

CNS Neurosci Ther
Çelik F.
europepmc   +1 more source

Oxidative Stress: Signaling Pathways, Biological Functions, and Disease

MedComm, Volume 6, Issue 7, July 2025.
Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu, Jiachen Liu, Yinhuai Wang, Fei Deng, Zebin Deng   +4 more
wiley   +1 more source

Cellular defenses against excitotoxic insults [PDF]

, 2001
Robert M. Sapolsky
openalex   +1 more source

Kynurenines and Mitochondrial Disturbances in Multiple Sclerosis. [PDF]

Int J Mol Sci
Pukoli D, Vécsei L.
europepmc   +1 more source

Therapeutic Targeting of the α7 Nicotinic Receptor: Challenges and Prospects for Cognitive Improvement in Alzheimer's and Schizophrenia

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 1, July 2025.
ABSTRACT The α7 nicotinic acetylcholine receptor (α7 nAChR) has emerged as a key target for treating cognitive dysfunction in neurological disorders such as Alzheimer's disease (AD) and schizophrenia. α7 nAChRs play essential roles in neurotransmission, neuroinflammation and synaptic plasticity, not only in neurons but also in glial cells, where they ...
Janus H. Magnussen
wiley   +1 more source