Results 251 to 260 of about 83,508 (337)

Scutellarin Protects Retinal Ganglion Cells in Glaucoma by Targeting the Hsp90aa1-MAPK Pathway to Inhibit Apoptosis. [PDF]

Invest Ophthalmol Vis Sci
Su JZ, Wang J, Gao ZL, Ding L, Xia XB.
europepmc   +1 more source

Dehydroepiandrosterone sulfate is neuroprotective in a focal cortical cold lesion model [PDF]

, 2007
Farkas, Tamás, Juhász-Vedres, Gabriella, Kis, Zsolt, Rákos, Gabriella, Rózsa, Éva, Toldi, József, Wölfling, János   +6 more
core  

The Role of Sphingolipid Metabolism and Neuron Death in Ischemic Stroke: A New Perspective from Bioinformatics

Brain and Behavior, Volume 16, Issue 1, January 2026.
First, we evaluated of differences in sphingolipid metabolism using peripheral blood samples from IS patients and healthy controls. Then, we identify the hub genes linking sphingolipid metabolism and neuronal death via modular analysis of protein‐protein interaction networks.
Zhong‐can Chen, Fang‐biao Xu, Sen Hu, Qiang Cui, Hugo Andrade Barazarte, Jing Zhang, Li‐na Suo, Jian‐jun Gu, Jiang‐yu Xue   +8 more
wiley   +1 more source

Losing the Filter: How Kynurenine Pathway Dysregulation Impairs Habituation. [PDF]

Cells
de la Flor MA, O'Connor JC.
europepmc   +1 more source

Research Progress of Ferroptosis in Cerebral Infarction

Brain and Behavior, Volume 16, Issue 1, January 2026.
Cerebral infarction triggers ischemia–reperfusion injury, leading to iron overload, oxidative stress, and mitochondrial dysfunction, which together initiate ferroptosis—an iron‐dependent, lipid peroxidation–driven form of neuronal death. Disruption of the System Xc−/GSH/GPX4 antioxidant axis and ACSL4‐mediated PUFA phospholipid enrichment accelerates ...
Yilan Fei, Qi Leng
wiley   +1 more source

Biochanin A prevents neurodegeneration and oxidative stress in a kainic acid model of epilepsy by activating the PI3K/Akt/Nrf2 signaling pathway. [PDF]

Sci Rep
Kongsui R, Promsrisuk T, Chanmanee T, Klimaschewski L, Jamsuwan S, Sriraksa N, Jittiwat J, Thongrong S.   +7 more
europepmc   +1 more source

Lineage‐Biased Neural Stem Cell Grafting Promotes Neuronal Differentiation and Vascular Repair in the Chronic Phase of Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Schematic diagram comparing two differentiation strategies to generate NSCs. The nEB‐NSCs exhibited a pronounced bias toward neuronal lineage differentiation. Transplantation of nEB‐NSCs into stroke mice (induced by tMCAO surgery) promoted motor recovery and vascular repair.
Tingting Zhang, Da Li, Qibiao Guan, Bin An, Yun Sun, Qiang Wang, Yukai Wang, Baoyang Hu   +7 more
wiley   +1 more source

Inhibition of Mettl3-mediated m6A RNA modification of HMGCS1 protects retinal ganglion cells from glutamate excitotoxicity-induced ferroptosis in a rat model of glaucoma. [PDF]

Int J Surg
Wang C, Feng L, Fang W, Zhang C, Zhang W, Zhu W, He Y, Xia Z, Song W, Xia X.   +9 more
europepmc   +1 more source

Exploring the Fecal Microbiome Dysbiosis and Its Plasma Metabolome Determinants in Advanced Parkinson's Disease With Motor Complications

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Our multiomics analysis across three PD cohorts revealed distinct fecal microbiome and plasma metabolome alterations in patients with motor complications (PD‐MC). We identified specific microbial and metabolic biomarkers and uncovered significant correlations between them, providing new insights into PD‐MC pathophysiology. ABSTRACT Background Parkinson'
Shuangjie Qian, Jialong Hou, Xi Xiong, Qi Duan, Tao Jiang, Yi Zheng, Weiwei Quan, Jiaxue Xu, Keke Chen, Jingjing Qian, Hongchang Gao, Chenglong Xie   +11 more
wiley   +1 more source