Results 1 to 10 of about 622,707 (285)
Demethyleneberberine is an active component extracted from the Chinese herbal drug Cortex Phellodendri. It is also a metabolite of berberine in animals and humans.
Jingqi Li +4 more
doaj +1 more source
Pharmacokinetics, bioavailability, and excretion of ponazuril in piglets
Ponazuril is a triazine anticoccidial drug which is the main metabolite of toltrazuril in animals, it has excellent activity against many protozoa, including Cystoisospora suis, and has broad application prospects in the control of swine coccidiosis.
Wenxiang Wang +10 more
doaj +1 more source
Exploring the potential hazard of Mycobacterium avium subspecies paratuberculosis as a cause for Crohn's disease [PDF]
Background: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease (JD), or paratuberculosis in ruminants has been suspected to be implicated in the pathogenesis of Crohn's disease (CD) in humans with chronic ...
Sukumar Bharathy +2 more
doaj +1 more source
Zapnometinib is a MEK inhibitor currently under clinical development for the treatment of COVID-19 and influenza. Zapnometinib has both antiviral and immunomodulatory effects. Information concerning the absorption, distribution, metabolism, and excretion
Yvonne Füll +5 more
doaj +1 more source
Regulation Mechanisms of Expression and Function of Organic Cation Transporter 1
The organic cation transporter 1 (OCT1) belongs together with OCT2 and OCT3 to the solute carrier family 22 (SLC22). OCTs are involved in the movement of organic cations through the plasma membrane.
Giuliano Ciarimboli
doaj +1 more source
Sugar intake among German adolescents: trends from 1990-2016 based on biomarker excretion in 24-h urine samples [PDF]
Trend analyses based on dietary records suggest decreases in the intakes of total (TS), added (AS) and free sugar (FS) since 2005 among children and adolescents in Germany. In terms of age trends, TS intake decreased with increasing age.
Alexy, Ute +5 more
core +1 more source
The aim of the study is the investigation of the pharmacokinetic properties of the RU-1205 compound, with previously identified kappa-agonistic and analgesic effects, at a single oral administration, as well as comparison of the relationship between its ...
A. A. Spasov +8 more
doaj +1 more source
Measurement of Fecal Testosterone Metabolites in Mice: Replacement of Invasive Techniques [PDF]
Testosterone is the main reproductive hormone in male vertebrates and conventional methods to measure testosterone rely on invasive blood sampling procedures.
Auer, Kerstin E. +5 more
core +1 more source
Paeonol is a major bioactive ingredient in Moutan Cortex (the root barks of Paeonia suffruticosa Andrews) and exhibited a wide range of bioactivities such as anti-inflammation, anti-oxidation, hypoglycemic effect, analgesic, and others.
Xintong Hu +14 more
doaj +1 more source
Urinary porphyrin excretion in hepatitis C infection [PDF]
A high prevalence of hepatitis C virus infection in porphyria cutanea tarda in some populations suggests a close link between viral hepatitis and alteration of porphyrin metabolism.
Jacob, Karl +2 more
core +1 more source

