Results 21 to 30 of about 622,707 (285)
Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]
, 2018 BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila +6 more
core +2 more sources
Pharmaceutics, 2021 Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) is a free radical scavenger approved for the treatment of amyotrophic lateral sclerosis, a fatal neuromuscular disease. Edaravone is administered as an intravenous infusion over 60 min for several treatment
Dong Wook Kang +9 more
doaj +1 more source
The Effects of Intraspecific Variation of Crayfish Behavior on Nutrient Cycling in Aquatic Environments [PDF]
, 2020 Human activities are rapidly altering species traits at a global scale. Yet, there remains a critical need to determine whether trait variation within species affects ecosystem responses to global change. In particular, intraspecific variation in feeding
Acheson, Paul
core
Drug Design, Development and Therapy, 2021 Kai Pan,1,2 Xiaolei Shi,2 Kai Liu,3 Ju Wang,2 Yijun Chen1 1State Key Laboratory of Natural Medicines and Laboratory of Chemical Biology, China Pharmaceutical University, Nanjing, Jiangsu Province, 211198, People’s Republic of China; 2Jiangsu Hengrui ...
Pan K, Shi X, Liu K, Wang J, Chen Y
doaj
Nanomaterials, 2023 To improve the efficacy of nanoparticles (NPs) and boost their theragnostic potential for brain diseases, it is key to understand the mechanisms controlling blood–brain barrier (BBB) crossing.
Ornella Muscetti +4 more
doaj +1 more source
New Marker of Colon Cancer Risk Associated with Heme Intake: 1,4-Dihydroxynonane Mercapturic Acid [PDF]
, 2006 Background: Red meat consumption is associated with an increased risk of colon cancer. Animal studies show that heme, found in red meat, promotes preneoplastic lesions in the colon, probably due to the oxidative properties of this compound.
Bingham, Sheila A. +8 more
core +4 more sources
Renal Failure, 2018 In most countries, salt intake has been excessive and constitutes one of the main risk factors for disease development, especially hypertension. Factors such as age, gender, sedentary lifestyle, smoking, African descent, obesity, dietary habits and ...
Elisângela Milhomem dos Santos +7 more
doaj +1 more source
Excretion of Vancomycin-Resistant Enterococci by Wild Mammals
Emerging Infectious Diseases, 2002 A survey of fecal samples found enterococcal excretion in 82% of 388 bank voles (Clethrionomys glareolus), 92% of 131 woodmice (Apodemus sylvaticus), and 75% of 165 badgers (Meles meles). Vancomycin-resistant enterococci, all Enterococcus faecium of vanA
David J. P. Mallon +6 more
doaj +1 more source
Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis [PDF]
, 2017 The effect of a sodium glucose cotransporter 2 inhibitor (SGLT2i) in reducing heart failure hospitalization in the EMPA-REG OUTCOMES trial has raised the possibility of using these agents to treat established heart failure.
De Vecchis +22 more
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Frontiers in Physiology, 2012 In insects, Malpighian tubules are functionally analogous to mammalian kidneys in that they not only are essential to excrete waste molecules into the lumen but also are responsible for the reabsorption of indispensable molecules, such as sugars, from ...
Shingo eKikuta +5 more
doaj +1 more source