Results 21 to 30 of about 582,301 (339)

Exploring the potential hazard of Mycobacterium avium subspecies paratuberculosis as a cause for Crohn's disease [PDF]

open access: yesVeterinary World, 2017
Background: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease (JD), or paratuberculosis in ruminants has been suspected to be implicated in the pathogenesis of Crohn's disease (CD) in humans with chronic ...
Sukumar Bharathy   +2 more
doaj   +1 more source

Impact of Particle Size on Toxicity, Tissue Distribution and Excretion Kinetics of Subchronic Intratracheal Instilled Silver Nanoparticles in Mice

open access: yesToxics, 2022
The unique physicochemical properties of silver nanoparticles (AgNPs) make them useful in a wide range of sectors, increasing their propensity for human exposure, as well as the need for thorough toxicological assessment.
Fernanda Rosário   +6 more
doaj   +1 more source

Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women

open access: yesEuropean Heart Journal, 2018
AIMS Carnitine and choline are major nutrient precursors for gut microbiota-dependent generation of the atherogenic metabolite, trimethylamine N-oxide (TMAO).
Zeneng Wang   +11 more
semanticscholar   +1 more source

Pharmacokinetics, Tissue Distribution and Excretion of Paeonol and Its Major Metabolites in Rats Provide a Further Insight Into Paeonol Effectiveness

open access: yesFrontiers in Pharmacology, 2020
Paeonol is a major bioactive ingredient in Moutan Cortex (the root barks of Paeonia suffruticosa Andrews) and exhibited a wide range of bioactivities such as anti-inflammation, anti-oxidation, hypoglycemic effect, analgesic, and others.
Xintong Hu   +14 more
doaj   +1 more source

Pharmacokinetics, Tissue Distribution and Excretion of Demethyleneberberine, a Metabolite of Berberine, in Rats and Mice

open access: yesMolecules, 2023
Demethyleneberberine is an active component extracted from the Chinese herbal drug Cortex Phellodendri. It is also a metabolite of berberine in animals and humans.
Jingqi Li   +4 more
doaj   +1 more source

A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome

open access: yesJournal of Clinical Investigation, 2019
An excess of fecal bile acids (BAs) is thought to be one of the mechanisms for diarrhea-predominant irritable bowel syndrome (IBS-D). However, the factors causing excessive BA excretion remain incompletely studied.
Ling Zhao   +27 more
semanticscholar   +1 more source

Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study

open access: yesBritish medical journal, 2019
Objective To evaluate the joint association of sodium and potassium urinary excretion (as surrogate measures of intake) with cardiovascular events and mortality, in the context of current World Health Organization recommendations for daily intake (3.5 g ...

semanticscholar   +1 more source

Time course of changes in 6-sulfatoxymelatonin excretion in patients with breast cancer after various neoadjuvant chemotherapy options

open access: yesОпухоли женской репродуктивной системы, 2014
The level of the metabolite 6-sulfatoxymelatonin (6-SOM) was studied on automedia before and after neoadjuvant systemic polyche- motherapy and neoadjuvant chemotherapy.
Yu. S. Sidorenko   +3 more
doaj   +1 more source

Developmental Pharmacokinetics of Antibiotics Used in Neonatal ICU: Focus on Preterm Infants

open access: yesBiomedicines, 2023
Neonatal Infections are among the most common reasons for admission to the intensive care unit. Neonatal sepsis (NS) significantly contributes to mortality rates.
Olga I. Butranova   +3 more
doaj   +1 more source

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