Results 81 to 90 of about 423,800 (304)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Identification of the fecal metabolites of 17α-methyltestosterone in the dog
Journal of Lipid Research, 1968 1 7α-Methyltestosterone-4-14C was fed to two dogs in an experiment to determine tissue localization and metabolic disposition of this hypocholesterolemic steroid.
Erwin H. Mosbach +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Insects, 2013 We performed a sequestration study of aristolactams (ALs) from Aristolochia chilensis in Battus polydamas archidamas (Lepidoptera: Papilionidae) by examining the AL content of the plant, fifth instar larvae, osmeterial secretion, pupae, exuviae and feces.
Angel Olguín +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Vers une révision de la norme de production d'azote de la vache laitière : justification et conséquences sur le taux de liaison au sol des exploitations laitières [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2010 Towards a revison of the dairy cow’s standard for nitrogen production: justification and what are consequences for soil link rate of dairy farms. At present, the dairy cow’s standard of nitrogen production in Walloon region is 90 kg per year.
Lambert R. +5 more
doaj
Pharmacokinetics, Tissue Distribution and Excretion of Verticinone from F. hupehensis in Rats
Molecules, 2014 Verticinone, the main active component in F. hupehensis, exhibits potent antitussive and expectorant effects. Here, a LC-MS method was developed and applied to study the pharmacokinetics, tissue distribution and excretion of verticinone in rats, and its ...
Xiao Wu +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
The role of the cAMP/PKA and cGMP/PKG pathways in the regulation of the transbranchial ammonia excretion in the green shore crab, Carcinus maenas [PDF]
As a toxic nitrogenous waste, ammonia causes ionoregulatory and neuronal dysfunction in aquatic animals. Without mechanisms to convert ammonia into less toxic molecules such as urea and uric acid, ammonotelic animals excrete ammonia directly into the ...
ZHANG, BAOYUE
core
Molecules, 2018 Ziyuglycoside I (ZGS1) is a promising drug candidate for the treatment of leucopenia. Currently, information on ZGS1 and its in vivo metabolite ziyuglycoside II (ZGS2) is limited.
Zhi-Feng Li +9 more
doaj +1 more source