Results 41 to 50 of about 2,829,937 (292)
Potchefstroom Electronic Law Journal, 2012 This article takes as its starting point a controversy which has arisen around a proposed assessment by the South African government of the decisions of the Constitutional Court, giving rise to concerns that this will constitute undue interference with ...
David Hulme, Stephen Peté
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Координирачки улоги на извршната власт како варијабли кои ги оцртуваат безбедносните релации во Република Македонија [PDF]
Bezbednosni Dijalozi, 2013 This paper counterpoises an analysis of the coordinating roles of the executive in the effectuation of the needed coordination of the security sector in the Republic of Macedonia.
Oliver BAKRESKI, Stojan Slaveski
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Attention Networks and Consciousness
Frontiers in Psychology, 2012 The term consciousness is an important one in the vernacular of the western literature in many fields. It is no wonder that scientists have assumed that consciousness will be found as a component of the human brain and that we will come to understand ...
Michael ePosner
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
An interpreter advantage in executive functions? A systematic review [PDF]
, 2020 The aim of this systematic literature review was to answer the question of which executive function is most affected by interpreter training and experience.
Hollebeke, Illy +4 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Executive Compensation and the Cost of Debt [PDF]
, 2010 We examine how executive compensation affects the cost of debt financing. Analyzing CEO pay data from the UK, we find that debt-like and equity-like pay components have opposite effects on the cost of debt.
Kabir, Rezaul +2 more
core +4 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
ON ROLE AND CONTRIBUTION OF THE CONSEIL D’ETAT IN LEGISLATION
Zbornik Radova Pravnog Fakulteta u Splitu, 2008 During the 20th century, throughout the Western world, a process of democratisation (legislative) of delegation occurred in a way which is consistent with the specifi c historical experience and constitutional traditions of each country in particular ...
Petar Bačić
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